Most Read Articles
Roshini Claire Anthony, 3 days ago

The presence of pulmonary arterial hypertension (PAH) in individuals with systemic sclerosis is associated with an increased mortality risk, a study from Singapore showed.

23 Dec 2019
At a Menarini-sponsored symposium held during the Asian Pacific Society Congress, renowned cardiologist Prof John Camm provided the latest evidence for chronic stable angina with or without concomitant diseases, with a special focus on the antianginal agent ranolazine and combination therapies. The event was chaired and moderated by Dr Dante Morales from the University of the Philippines College of Medicine.
3 days ago
Serum 25-hydroxyvitamin D (25[OH]D) levels are significantly lower among patients with active uveitis than those with inactive uveitis and local population-based estimates, reports a study. In addition, vitamin D supplementation may help reduce uveitis activity, while sun exposure confers a beneficial effect to those with vitamin D deficiency.
2 days ago
The timing of direct oral anticoagulants (DOACs) administration, either within 3 days or ≥4 days of stroke onset, in patients with nonvalvular atrial fibrillation (AF) does not alter the risk of adverse outcomes such as stroke or systemic embolism, major bleeding, and death, as shown in a recent study.

Preoperative atorvastatin does not improve erectile function recovery after prostatectomy

03 Oct 2019

A short-term course of atorvastatin prior to radical prostatectomy does not yield significant benefits on the recovery of erectile function after the procedure, a recent study has found.

Participants randomly received either 80-mg atorvastatin (n=60; median age, 64 years) or placebo (n=58; median age, 64 years) on a daily basis before undergoing radical prostatectomy. Erectile function was assessed using the International Index of Erectile Function (IIEF-5) questionnaire before surgery and 3, 6, 9 and 12 months after.

At baseline, normal erectile function was reported in 43 percent of men in the statin arm and in 45 percent in the placebo arm. These proportions shrank to 4 percent and 2 percent 3 months after surgery, respectively. By 12 months, the rate of normal erectile function rebounded slightly to 9 percent in the statin group and 4 percent in the placebo group.

Conversely, severe erectile dysfunction rates ballooned to 78 percent and 90 percent in the statin and placebo arms, respectively, 3 months after surgery. Corresponding baseline rates were 8 percent and 4 percent.

At no point in the entire study duration were IIEF-5 scores significantly different between the study arms.

Subgroup analysis according to severity of erectile dysfunction, the use of nerve-sparing surgery, or baseline diabetes, hypertension or smoking did not change the initial results.

The present findings need confirmation in future, larger trials, said researchers. The effects of prolonged and postoperative statin use will also have to be investigated.

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Doctor - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
Roshini Claire Anthony, 3 days ago

The presence of pulmonary arterial hypertension (PAH) in individuals with systemic sclerosis is associated with an increased mortality risk, a study from Singapore showed.

23 Dec 2019
At a Menarini-sponsored symposium held during the Asian Pacific Society Congress, renowned cardiologist Prof John Camm provided the latest evidence for chronic stable angina with or without concomitant diseases, with a special focus on the antianginal agent ranolazine and combination therapies. The event was chaired and moderated by Dr Dante Morales from the University of the Philippines College of Medicine.
3 days ago
Serum 25-hydroxyvitamin D (25[OH]D) levels are significantly lower among patients with active uveitis than those with inactive uveitis and local population-based estimates, reports a study. In addition, vitamin D supplementation may help reduce uveitis activity, while sun exposure confers a beneficial effect to those with vitamin D deficiency.
2 days ago
The timing of direct oral anticoagulants (DOACs) administration, either within 3 days or ≥4 days of stroke onset, in patients with nonvalvular atrial fibrillation (AF) does not alter the risk of adverse outcomes such as stroke or systemic embolism, major bleeding, and death, as shown in a recent study.