Most Read Articles
29 Nov 2019
Metformin Extended Release 500 mg,750 mg, and 1000 mg
Pearl Toh, 2 days ago
Getting just under one extra hour of sleep per night can go a long way for the health of college students, who are often sleep-deprived, a study suggests.
29 Nov 2019
Saxagliptin 5 mg, dapagliflozin 10 mg FC tab
Roshini Claire Anthony, 6 days ago

The CA125* test could be useful at detecting ovarian cancer and various other cancers in the primary care setting, particularly for women aged >50 years, according to a study presented at the recent NCRI** Cancer Conference held in Glasgow, Scotland, UK.

Preoperative atorvastatin does not improve erectile function recovery after prostatectomy

03 Oct 2019

A short-term course of atorvastatin prior to radical prostatectomy does not yield significant benefits on the recovery of erectile function after the procedure, a recent study has found.

Participants randomly received either 80-mg atorvastatin (n=60; median age, 64 years) or placebo (n=58; median age, 64 years) on a daily basis before undergoing radical prostatectomy. Erectile function was assessed using the International Index of Erectile Function (IIEF-5) questionnaire before surgery and 3, 6, 9 and 12 months after.

At baseline, normal erectile function was reported in 43 percent of men in the statin arm and in 45 percent in the placebo arm. These proportions shrank to 4 percent and 2 percent 3 months after surgery, respectively. By 12 months, the rate of normal erectile function rebounded slightly to 9 percent in the statin group and 4 percent in the placebo group.

Conversely, severe erectile dysfunction rates ballooned to 78 percent and 90 percent in the statin and placebo arms, respectively, 3 months after surgery. Corresponding baseline rates were 8 percent and 4 percent.

At no point in the entire study duration were IIEF-5 scores significantly different between the study arms.

Subgroup analysis according to severity of erectile dysfunction, the use of nerve-sparing surgery, or baseline diabetes, hypertension or smoking did not change the initial results.

The present findings need confirmation in future, larger trials, said researchers. The effects of prolonged and postoperative statin use will also have to be investigated.

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Doctor - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
29 Nov 2019
Metformin Extended Release 500 mg,750 mg, and 1000 mg
Pearl Toh, 2 days ago
Getting just under one extra hour of sleep per night can go a long way for the health of college students, who are often sleep-deprived, a study suggests.
29 Nov 2019
Saxagliptin 5 mg, dapagliflozin 10 mg FC tab
Roshini Claire Anthony, 6 days ago

The CA125* test could be useful at detecting ovarian cancer and various other cancers in the primary care setting, particularly for women aged >50 years, according to a study presented at the recent NCRI** Cancer Conference held in Glasgow, Scotland, UK.