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Stephen Padilla, 23 Nov 2020
Fetoscopic laser ablation (FLP) is an effective treatment for twin-to-twin transfusion syndrome (TTTS) in monochorionic twin pregnancies, but it requires a tertiary neonatal facility and a highly specialized team in performing intervention therapies for the treatment of potential complications, according to a Singapore study.
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Serum folate levels during pregnancy correlate with the child’s neurodevelopment at 2 years of age, particularly in terms of language development, a recent study has shown. Folate supplementation may be a valuable nutritional intervention to consider.
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Prenatal tobacco exposure ups risk of paediatric psoriasis

05 Dec 2020

Prenatal exposure to tobacco is associated with an increased risk of paediatric psoriasis in a monotonic fashion, which suggests that smoking may contribute to psoriasis pathogenesis, suggest the results of a recent study.

Tobacco smoking had been implicated in psoriasis among adults. To determine whether prenatal, infantile, and childhood tobacco exposure heightened the risk of paediatric psoriasis, the investigators collected data from Danish National Birth Cohort participants at approximately gestational week 12 and when the children were about 6 months and 11 years of age.

A total of 25,812 offspring with complete data from the national birth cohort were included in the analysis. The odds of paediatric psoriasis with tobacco exposure prenatally, from birth to age 6 months (early infancy) and at age 11 years (childhood), were estimated.

Offspring with prenatal tobacco exposure had an increased risk of paediatric psoriasis (adjusted odds ratio [OR], 1.39, 95 percent confidence interval [CI], 1.06–1.82). An exposure–response relationship was also seen for increasing quantities of cigarettes smoked daily (≥16 cigarettes: adjusted OR, 2.92, 95 percent CI, 1.20–7.10; ptrend=0.038).

On the other hand, the associations of paediatric psoriasis with infantile (adjusted OR, 1.17, 95 percent CI, 0.76–1.79) and childhood (adjusted OR, 1.10, 95 percent CI, 0.77–1.58) tobacco exposure were attenuated after controlling for prenatal exposure.

The study was limited by the maternally reported outcome status, according to the investigators.

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Most Read Articles
Stephen Padilla, 23 Nov 2020
Fetoscopic laser ablation (FLP) is an effective treatment for twin-to-twin transfusion syndrome (TTTS) in monochorionic twin pregnancies, but it requires a tertiary neonatal facility and a highly specialized team in performing intervention therapies for the treatment of potential complications, according to a Singapore study.
18 Nov 2020
Serum folate levels during pregnancy correlate with the child’s neurodevelopment at 2 years of age, particularly in terms of language development, a recent study has shown. Folate supplementation may be a valuable nutritional intervention to consider.
18 Oct 2020
Girls with higher body fat percentage and whose parents smoke are likely to undergo precocious puberty, as reported in a study.