Most Read Articles
Kavitha G. Shekar, 12 Apr 2016

Cediranib combined with carboplatin and paclitaxel yields a longer progression-free survival in patients with metastatic or recurrent cervical cancer, say researchers.

21 Jan 2019
Caffeine intake from both coffee and tea during pregnancy may result in adverse birth outcomes, suggests a recent study.
31 Dec 2018

According to the Singapore Cancer Registry, ovarian cancer was the fifth most frequent cancer among women in Singapore and accounted for 5.4 percent of all female cancers diagnosed between 2011 and 2015, with an increasing incidence rate through the last four decades.

Audrey Abella, 01 Feb 2019
Voiding behaviour is associated with bladder problems in women, an exploratory analysis shows.

Pregnancy outcomes favourable for women with idiopathic noncirrhotic portal hypertension

25 Nov 2018
The study reaffirms that low-dose aspirin can be considered as a prophylactic of preterm delivery for women at high risk of preeclampsia

Despite condition-related complications, pregnancy in women with idiopathic noncirrhotic portal hypertension (INCPH) results in favourable foetal outcomes in a majority of cases reaching 20 weeks of gestation, reports a new study.

Researchers retrospectively reviewed the medical charts of 16 women with INCPH who had 1 pregnancy during the follow-up period for their liver disease. A total of 24 pregnancies were reported within a median of 24 months after INCPH diagnosis. All patients had serum bilirubin levels <2 mg/dL, and 75 percent had oesophageal varices upon diagnosis.

Over the median gestation duration of 35 weeks, one ectopic pregnancy, four miscarriages and one terminated pregnancy for medical reasons were reported. Eighteen pregnancies reached 20 weeks of gestation, of which one was born very preterm at 27 weeks. Eight were moderately preterm, while nine were term deliveries.

Two infant deaths were reported, one due to infectious meningitis and one due to unknown causes. Another infant had bradycardia during labour but was without sequelae, while another was born small for gestational age. All the other infants were born healthy and with appropriate birthweight.

Six portal hypertension-related complications were documented, including one case of worsening portopulmonary hypertension, three cases of worsening ascites and two cases of variceal bleedings.

No other liver-related complications were reported in the remaining 18 pregnancies. None of the participants developed liver failure or encephalopathy. All patients were asymptomatic at a median follow-up of 27 months after last delivery, and no maternal deaths occurred.

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Most Read Articles
Kavitha G. Shekar, 12 Apr 2016

Cediranib combined with carboplatin and paclitaxel yields a longer progression-free survival in patients with metastatic or recurrent cervical cancer, say researchers.

21 Jan 2019
Caffeine intake from both coffee and tea during pregnancy may result in adverse birth outcomes, suggests a recent study.
31 Dec 2018

According to the Singapore Cancer Registry, ovarian cancer was the fifth most frequent cancer among women in Singapore and accounted for 5.4 percent of all female cancers diagnosed between 2011 and 2015, with an increasing incidence rate through the last four decades.

Audrey Abella, 01 Feb 2019
Voiding behaviour is associated with bladder problems in women, an exploratory analysis shows.