Most Read Articles
Roshini Claire Anthony, 5 days ago

Individuals with moderate-to-severe plaque psoriasis may reap better long-term improvements in the severity of their condition when treated with guselkumab over secukinumab, according to findings of the phase III ECLIPSE* trial presented at the recent Inflammatory Skin Disease Summit (ISDS 2018) held in Vienna, Austria.

Jairia Dela Cruz, 11 Jan 2019
Use of standard-dose aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs) appears to confer protection against the risk of endometrial cancer in overweight and obese women, according to a meta-analysis.
4 days ago
Discontinuing the use of tyrosine kinase inhibitors (TKIs) in the treatment of patients with chronic myeloid leukaemia appears to be feasible in real-life clinical practice in the context of close molecular monitoring, a study reports.
5 days ago
There appears to be no clear link between pornography use, even at problematic levels, and erectile dysfunction, a recent US study has shown.

Prediabetes linked to impaired sexual functioning in men

23 Dec 2018

Prediabetes is likely to impair sexual functioning in young men, with the risk high in the presence of impairment of both fasting glucose and glucose tolerance, a study reports. Furthermore, sexual dysfunction is accompanied by mild depressive symptoms.

The study included four age- and weight-matched groups of apparently healthy men (25–50 years old), as follows: those with isolated impaired fasting glucose (IFG; n=16), those with isolated impaired glucose tolerance (IGT; n=17), those with both IFG and IGT (n=16), and controls with normal glucose tolerance (n=18). All men completed questionnaires that assessed sexual functioning (IIEF-15) and the presence and severity of depressive symptoms (BDI-II).

Fasting plasma glucose was higher in the IFG and IFG+IGT groups vs the IGT and control groups, whereas 2-h postchallenge plasma glucose was higher in the IGT and IFG+IGT groups vs the IFG and control groups. Furthermore, the homeostatic model for insulin resistance and triglycerides were higher, while HDL cholesterol was lower in the three prediabetic groups than in the control group.

Compared with controls, men in the IFG+IGT group achieved lower domain scores for erectile function, sexual desire and overall satisfaction, as well as the higher overall BDI-II score. Meanwhile, those with isolated IGT or IFG had lower domain score only for sexual desire.

There were correlations found between domain score for erectile function and the BDI-II score, and between scores for erectile function and sexual desire and degree of insulin resistance.

Given the small number of participants, the present data should be considered as pilot and confirmed in large clinical trials, researchers said.

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Doctor - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
Roshini Claire Anthony, 5 days ago

Individuals with moderate-to-severe plaque psoriasis may reap better long-term improvements in the severity of their condition when treated with guselkumab over secukinumab, according to findings of the phase III ECLIPSE* trial presented at the recent Inflammatory Skin Disease Summit (ISDS 2018) held in Vienna, Austria.

Jairia Dela Cruz, 11 Jan 2019
Use of standard-dose aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs) appears to confer protection against the risk of endometrial cancer in overweight and obese women, according to a meta-analysis.
4 days ago
Discontinuing the use of tyrosine kinase inhibitors (TKIs) in the treatment of patients with chronic myeloid leukaemia appears to be feasible in real-life clinical practice in the context of close molecular monitoring, a study reports.
5 days ago
There appears to be no clear link between pornography use, even at problematic levels, and erectile dysfunction, a recent US study has shown.