Most Read Articles
29 Nov 2017
Rapid onset opioids may allow for more effective treatment of breakthrough cancer pain as their pharmacokinetic profile closely mimics the pain’s time course
Stephen Padilla, 24 Oct 2017
Cancer drugs approved by the European Medicines Agency (EMA) from 2009 to 2013 have been sold in the market even without evidence of benefit on survival or quality of life (QoL), according to a study. Survival gains over existing treatment options or placebo, if any, are usually marginal.
Christina Lau, 22 Oct 2015
A 21-gene expression assay can identify patients with early-stage breast cancer who can skip adjuvant chemotherapy without facing an increased risk of recurrence at 5 years.
Dr Joslyn Ngu, 23 Nov 2017
Highlights from the Joint Cancer Genetics Meeting and the 15th International Meeting on the Psychosocial Aspects of Hereditary Cancer (IMPAHC) 2017

Prediabetes and diabetes increases hepatocellular carcinoma risk in Taiwanese men

Fiel Soliven
18 Mar 2015
The connection between prediabetes, diabetes, and risk of hepatocellular carcinoma (HCC) in HBsAg and anti-HCV seronegative patients, as well as the association between fasting glucose and HCC, was examined in this study. An initial 79,940 eligible residents participated in the present Keelung Community-Based Integrated Screening program, and were followed-up between 1999 and 2007.

Results showed that 114 individuals had developed HCC after 394,079 person-years follow-up. The adjusted hazard ratio was 1.59 for prediabetes, and 3.21 for diabetes, with males contributing to a majority of these associations. Prediabetes was also a significant predictor in those with lower total cholesterol, lower low-density-lipoprotein-cholesterol and never smokers. HCC risk was observed to increase rapidly at fasting glucose level of 85 mg/dL in males, showing a non-linear trend. Providing interventions as soon as the detection of prediabetes in males may therefore lessen the risk for HCC.
Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Oncology - Malaysia digital copy today!
DOWNLOAD
Editor's Recommendations
Most Read Articles
29 Nov 2017
Rapid onset opioids may allow for more effective treatment of breakthrough cancer pain as their pharmacokinetic profile closely mimics the pain’s time course
Stephen Padilla, 24 Oct 2017
Cancer drugs approved by the European Medicines Agency (EMA) from 2009 to 2013 have been sold in the market even without evidence of benefit on survival or quality of life (QoL), according to a study. Survival gains over existing treatment options or placebo, if any, are usually marginal.
Christina Lau, 22 Oct 2015
A 21-gene expression assay can identify patients with early-stage breast cancer who can skip adjuvant chemotherapy without facing an increased risk of recurrence at 5 years.
Dr Joslyn Ngu, 23 Nov 2017
Highlights from the Joint Cancer Genetics Meeting and the 15th International Meeting on the Psychosocial Aspects of Hereditary Cancer (IMPAHC) 2017