Most Read Articles
6 days ago
Intravenous (IV) iron is less toxic and more effective compared to oral iron, making it a potential frontline therapy for neonatal iron deficiency anaemia, suggests a recent study.
Shilpa Kolhe, MBBS, MD, MRCOG; Shilpa Deb, MBBS, DGO, MRCOG, 01 Aug 2012

Dysmenorrhoea is a medical condition characterized by severe uterine pain during menstruation manifesting as cyclical lower abdominal or pelvic pain, which may also radiate to the back and thighs. The term dysmenorrhoea is derived from the Greek words ‘dys’ meaning difficult, painful or abnormal, ‘meno’ meaning month, and ‘rrhea’ meaning flow. It is commonly divided into primary dysmenorrhoea, where there is no coexistent pathology, and secondary dysmenorrhoea where there is an identifiable pathological condition known to contribute to painful menstruation. Symptoms of primary dysmenorrhoea begin a few hours before the start of menstruation and are often relieved during the first few days of bleeding. The initial onset of primary dysmenorrhoea is usually shortly after menarche (6–12 months), when ovulatory cycles are established. Secondary dysmenorrhoea can also occur at any time after menarche but is most commonly observed in women in their third and fourth decade of life in association with an existing condition.

02 Dec 2014
Adolescent females often experience menstrual problems, and these are usually related to mood changes. In this study, the association between dysmenorrhea and depressive symptoms, anxiety, and premenstrual syndrome was examined.
26 Feb 2017
Placement of cervical pessary in women with short cervices and singleton pregnancies does not lower the risk of having preterm births, according to the results of a meta-analysis.

Pre-eclampsia mediates effect of short maternal stature on preterm delivery risk

31 Jul 2017

Women with shorter height are at increased risk of preterm delivery, with the effect of height on the risk partially mediated by pre-eclampsia, a study suggests.

A total of 218,412 women who delivered singleton pregnancies and who had no underlying diseases before pregnancy were assessed for the risk of preterm delivery in relation to height and how the association was mediated by the risk of pre-eclampsia. All women were included in the Japan Society of Obstetrics and Gynecology, a national multicentre-based delivery database among tertiary hospitals.

Results showed that every 5-cm decrement in height was associated with shorter gestational age (−0.30 weeks; 95 percent CI, -0.44 to -0.16) and significantly increased risk of preterm delivery (relative risk, 1.20; 1.13 to 1.27).

Mediation analysis demonstrated that the effect of shorter height on increased risk of preterm delivery, which was attributed to an indirect effect mediated through increased risk of pre-eclampsia, was notable for shorter gestational age (48 percent), as well as risk of preterm delivery (28 percent).

In an analysis stratified by the three subtypes of preterm delivery, the mediated effect was most pronounced for provider-initiated preterm delivery without premature rupture of membranes (PROM; 34 percent) vs spontaneous preterm delivery without PROM (17 percent) or preterm delivery with PROM (0 percent).

Interpretation of the associations between maternal height and pregnancy outcomes has been based upon a mechanistic assumption that maternal height establishes a physical constraint on the intrauterine environment, such that shorter women may have a small uterus size which in turn limits foetal growth. [J Pediatr 2007;150:603–7]

Additionally, adult height may reflect a mother’s cumulative social and nutritional condition over her life course, serving as potential indicator of the persisting biological and/or environmental factors which affect the offspring’s growth in utero. [JAMA 2009;301:1691–701]

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Most Read Articles
6 days ago
Intravenous (IV) iron is less toxic and more effective compared to oral iron, making it a potential frontline therapy for neonatal iron deficiency anaemia, suggests a recent study.
Shilpa Kolhe, MBBS, MD, MRCOG; Shilpa Deb, MBBS, DGO, MRCOG, 01 Aug 2012

Dysmenorrhoea is a medical condition characterized by severe uterine pain during menstruation manifesting as cyclical lower abdominal or pelvic pain, which may also radiate to the back and thighs. The term dysmenorrhoea is derived from the Greek words ‘dys’ meaning difficult, painful or abnormal, ‘meno’ meaning month, and ‘rrhea’ meaning flow. It is commonly divided into primary dysmenorrhoea, where there is no coexistent pathology, and secondary dysmenorrhoea where there is an identifiable pathological condition known to contribute to painful menstruation. Symptoms of primary dysmenorrhoea begin a few hours before the start of menstruation and are often relieved during the first few days of bleeding. The initial onset of primary dysmenorrhoea is usually shortly after menarche (6–12 months), when ovulatory cycles are established. Secondary dysmenorrhoea can also occur at any time after menarche but is most commonly observed in women in their third and fourth decade of life in association with an existing condition.

02 Dec 2014
Adolescent females often experience menstrual problems, and these are usually related to mood changes. In this study, the association between dysmenorrhea and depressive symptoms, anxiety, and premenstrual syndrome was examined.
26 Feb 2017
Placement of cervical pessary in women with short cervices and singleton pregnancies does not lower the risk of having preterm births, according to the results of a meta-analysis.