Most Read Articles
Pearl Toh, 31 Dec 2019
Adding the neuraminidase inhibitor oseltamivir to usual care speeds up recovery from influenza-like illness by a day compared with usual care alone, with even greater benefits seen in older, sicker patients with comorbidities, according to the ALIC4E study.
23 Dec 2019
At a Menarini-sponsored symposium held during the Asian Pacific Society Congress, renowned cardiologist Prof John Camm provided the latest evidence for chronic stable angina with or without concomitant diseases, with a special focus on the antianginal agent ranolazine and combination therapies. The event was chaired and moderated by Dr Dante Morales from the University of the Philippines College of Medicine.
Pearl Toh, 5 days ago
Obeticholic acid significantly improves fibrosis and disease activity in patients with nonalcoholic steatohepatitis (NASH), a chronic liver disease currently with no approved therapy, according to an interim analysis of the landmark REGENERATE* study.
6 days ago
Testosterone treatment may slightly improve sexual functioning and quality of life in men without underlying organic causes of hypogonadism, but it offers little to no benefit for other common symptoms of ageing, according to a study. In addition, long-term efficacy and safety of this therapy remain unknown.

Pre-eclampsia carries increased risk of cardiovascular disorders

01 Nov 2019

Women with hypertensive disorders of pregnancy, especially pre-eclampsia, are at heightened risk of developing cardiovascular disorder and chronic hypertension, with the risk becoming apparent soon after pregnancy, a study has found.

Researchers looked at a UK population-based cohort of 1.3 million women (mean age at delivery, 28 years) with nearly 1.9 million completed pregnancies. A total of 18,624 incident cardiovascular disorders were recorded over the 20-year study period, and 65 percent of these events occurred in women aged <40 years.

Relative to women without hypertension in pregnancy, those who had one or more pregnancies affected by pre-eclampsia were more likely to develop any stroke (hazard ratio [HR], 1.9, 95 percent CI, 1.53–2.35), cardiac atherosclerotic events (HR, 1.67, 1.54–1.81), peripheral events (HR, 1.82, 1.34–2.46), heart failure (HR, 2.13, 1.64–2.76), atrial fibrillation (HR, 1.73, 1.38–2.16), cardiovascular deaths (HR, 2.12, 1.49–2.99) and chronic hypertension (HR, 4.47, 4.32–4.62).

Differences in cumulative incidence curves in the group of women with vs without pre-eclampsia were evident within 1 year of the first index pregnancy. Similar patterns of association were observed for hypertensive disorders of pregnancy, whereas preterm pre-eclampsia was associated with slightly higher risks.

In light of the findings, the researchers suggest that hypertensive disorders of pregnancy be considered as a natural screening tool for cardiovascular events, enabling cardiovascular risk prevention through national initiatives.

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Doctor - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
Pearl Toh, 31 Dec 2019
Adding the neuraminidase inhibitor oseltamivir to usual care speeds up recovery from influenza-like illness by a day compared with usual care alone, with even greater benefits seen in older, sicker patients with comorbidities, according to the ALIC4E study.
23 Dec 2019
At a Menarini-sponsored symposium held during the Asian Pacific Society Congress, renowned cardiologist Prof John Camm provided the latest evidence for chronic stable angina with or without concomitant diseases, with a special focus on the antianginal agent ranolazine and combination therapies. The event was chaired and moderated by Dr Dante Morales from the University of the Philippines College of Medicine.
Pearl Toh, 5 days ago
Obeticholic acid significantly improves fibrosis and disease activity in patients with nonalcoholic steatohepatitis (NASH), a chronic liver disease currently with no approved therapy, according to an interim analysis of the landmark REGENERATE* study.
6 days ago
Testosterone treatment may slightly improve sexual functioning and quality of life in men without underlying organic causes of hypogonadism, but it offers little to no benefit for other common symptoms of ageing, according to a study. In addition, long-term efficacy and safety of this therapy remain unknown.