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Potassium- and magnesium-enriched salt improves functionality after stroke

15 Nov 2017

Enriching salt with both potassium and magnesium in the long term may provide additional benefits for stroke patient recovery from neurologic deficits, suggests a recent study involving Taiwanese patients.

A total of 291 discharged stroke patients with modified Rankin scale (mRS) ≤4 were randomly assigned to one of three arms: 1) regular salt (Na salt; n=99), 2) potassium-enriched salt (K salt; n=97), and 3) potassium- and magnesium-enriched salt (K/Mg salt; n=95).

The investigators evaluated the NIH Stroke Scale (NIHSS), Barthel Index (BI) and mRS at discharge, at 3 months and at 6 months. A good neurologic performance was defined by NIHSS=0, BI=100 and mRS ≤1.

More patients in the K/Mg salt group achieved good neurologic performance than in the K salt group and the Na salt group, in that order, after the 6-month intervention. The K/Mg salt group had a significantly increased odds ratio (OR; 2.22; 95 percent CI, 1.09 to 4.67) of achieving good neurologic performance compared with the Na salt group. However, the effect of K salt alone (OR, 1.58; 0.77 to 3.22) was not significant.

“Stroke is one of the leading causes of mortality and neurologic deficits. Management measures to improve neurologic outcomes are in great need,” the investigators said. “Our previous intervention trial in elderly [individuals] successfully used salt as a carrier for potassium, demonstrating a 41-percent reduction in cardiovascular mortality by switching to potassium-enriched salt.”

“Dietary magnesium has been associated with lowered diabetes and/or stroke risk in humans and with neuroprotection in animals,” they added.

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Most Read Articles
15 Nov 2017
Men with breast cancer have tumours that are typically of the human epidermal growth factor receptor 2-negative Luminal B subtype and positive for oestrogen receptor, progesterone receptor and androgen receptor, according to the results of the EORTC 10085/TBCRC/BIG/NABCG International Male Breast Cancer Program study.
Yesterday
Long-term use of benzodiazepines is independently associated with lower diastolic and systolic blood pressure in ambulatory blood pressure monitoring (ABPM) among older but not younger patients, a study has found.
3 days ago
There appears to be a paradox in the context of smoking and the risk of psoriatic arthritis (PsA), such that current smoking increases the risk of developing PsA in the general population but protects against the same risk among patients with psoriasis, according to a study.
4 days ago
Moderate increases in physical activity levels may translate to significant reductions in both fasting glucose and HbA1c, a study has found.