Most Read Articles
Roshini Claire Anthony, 11 Sep 2019

Beta-blockers could reduce mortality risk in patients with heart failure with reduced ejection fraction (HFrEF) and moderate or moderately-severe renal dysfunction without causing harm, according to the BB-META-HF* trial presented at ESC 2019.

Prof. Vincent Wong, Prof. Ray Kim, Dr. Tan Poh Seng, 10 Sep 2019
Chronic hepatitis B (CHB) remains a major public health concern because of its worldwide distribution and potential adverse sequelae, including cirrhosis and hepatocellular carcinoma (HCC). At a recent symposium held during the GIHep Singapore 2019, Professor Vincent Wong from the Chinese University of Hong Kong and Professor Ray Kim from the Stanford University School of Medicine, Stanford, California, US, discussed antiviral treatments for CHB, with a focus on the novel agent tenofovir alafenamide (Vemlidy®). Dr Tan Poh Seng from the National University Hospital, Singapore, chaired the symposium.
11 Sep 2019
Blood pressure (BP) in children is influenced by early-life exposure to several chemicals, built environment and meteorological factors, suggests a study.
Pearl Toh, Yesterday
The use of SGLT-2* inhibitors was not associated with a higher risk of severe or nonsevere urinary tract infections (UTIs) in patients with type 2 diabetes (T2D) compared with DPP**-4 inhibitors or GLP-1*** receptor agonists, a population-based cohort study shows.

Postpartum mental disorders entail increased risk of self-harm

13 Aug 2019

Women with postpartum mental disorders (PPMD) are more likely to inflict self-harm than mothers without a history of psychiatric diagnosis and treatment, a study has found.

The study included 1,202,292 Danish women, of whom 1,554 women had severe first-onset PPMD, defined as experiencing first psychiatric outpatient or inpatient contact to a psychiatric facility within 90 days after delivering their first child. Sixty-four women with PPMD had a first-ever hospital record of self-harm following their diagnosis.

In the group of PPMD patients who had inflicted self-harm, 20 were diagnosed with anxiety or stress-related mental disorders (31.3 percent), 18 with affective mood disorders (28.1 percent), six (9.4 percent) with a schizophrenia or schizotypal disorder, and five (7.81 percent) with mental and behavioural disorders associated with the puerperium. The remaining 15 (23.43 percent) women had other diagnoses including personality disorders.

On Cox analysis, women with PPMD were six times as likely as mothers without mental disorders to inflict self-harm (hazard ratio [HR], 6.2, 95 percent CI, 4.9–8.0), although the risk was lower relative to that in mothers with mental disorders occurring outside the postpartum period (HR, 10.1, 9.6–10.5) and  in childless women with mental disorders (HR, 9.3, 8.9–9.7).

Of note, women with PPMD and records of self-harm had a significantly higher risk of later suicide compared with all other groups of women in the cohort.

The present data stress the importance of focusing on women with PPMD with a record of self-harm, as they represent a population with a significantly increased risk of subsequent suicide, the researchers said.

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Most Read Articles
Roshini Claire Anthony, 11 Sep 2019

Beta-blockers could reduce mortality risk in patients with heart failure with reduced ejection fraction (HFrEF) and moderate or moderately-severe renal dysfunction without causing harm, according to the BB-META-HF* trial presented at ESC 2019.

Prof. Vincent Wong, Prof. Ray Kim, Dr. Tan Poh Seng, 10 Sep 2019
Chronic hepatitis B (CHB) remains a major public health concern because of its worldwide distribution and potential adverse sequelae, including cirrhosis and hepatocellular carcinoma (HCC). At a recent symposium held during the GIHep Singapore 2019, Professor Vincent Wong from the Chinese University of Hong Kong and Professor Ray Kim from the Stanford University School of Medicine, Stanford, California, US, discussed antiviral treatments for CHB, with a focus on the novel agent tenofovir alafenamide (Vemlidy®). Dr Tan Poh Seng from the National University Hospital, Singapore, chaired the symposium.
11 Sep 2019
Blood pressure (BP) in children is influenced by early-life exposure to several chemicals, built environment and meteorological factors, suggests a study.
Pearl Toh, Yesterday
The use of SGLT-2* inhibitors was not associated with a higher risk of severe or nonsevere urinary tract infections (UTIs) in patients with type 2 diabetes (T2D) compared with DPP**-4 inhibitors or GLP-1*** receptor agonists, a population-based cohort study shows.