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Postnatal intervention cuts weight in overweight women with previous GDM

24 Jul 2018

A postnatal lifestyle intervention programme (PAIGE) for overweight women with previous gestational diabetes mellitus (GDM) leads to significantly greater weight loss compared with usual care at 6 months, a recent study has shown.

“Such weight loss could prove beneficial in terms of better long-term health and subsequent prevention of type 2 diabetes (T2D) in overweight women with previous GDM,” the authors said.

A total of 60 women were randomly assigned (29 intervention; 31 control) in two centres based on their week of attendance. Participants in the intervention group had significant weight loss at 6 months after randomization compared with those in the control group (mean, 3.9 vs 0.7 kg; p=0.02).

There was no significant difference in blood glucose levels. Furthermore, as regards measures of well-being, the intervention group showed significantly reduced bodily pain (p=0.007).

“Future interventions must consider recruitment strategies, timing of the intervention, and inclusion of partners and/or other family members,” the authors said.

In this study, postnatal overweight women with previous GDM were included in a multicentre randomized controlled trial between June 2013 and December 2014. The intervention consisted of a 1-hour educational programme, a free 3-month referral to a commercial weight management organization (Slimming World), a pedometer, and structured telephone and text support, in addition to usual care. The control group received usual care only. Weight loss at 6 months was the main outcome.

“GDM is associated with a sevenfold increased lifetime risk of T2D. Excessive gestational weight gain and postpartum weight retention are established predictors of long-term obesity,” the authors noted.

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