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Postnatal intervention cuts weight in overweight women with previous GDM

24 Jul 2018

A postnatal lifestyle intervention programme (PAIGE) for overweight women with previous gestational diabetes mellitus (GDM) leads to significantly greater weight loss compared with usual care at 6 months, a recent study has shown.

“Such weight loss could prove beneficial in terms of better long-term health and subsequent prevention of type 2 diabetes (T2D) in overweight women with previous GDM,” the authors said.

A total of 60 women were randomly assigned (29 intervention; 31 control) in two centres based on their week of attendance. Participants in the intervention group had significant weight loss at 6 months after randomization compared with those in the control group (mean, 3.9 vs 0.7 kg; p=0.02).

There was no significant difference in blood glucose levels. Furthermore, as regards measures of well-being, the intervention group showed significantly reduced bodily pain (p=0.007).

“Future interventions must consider recruitment strategies, timing of the intervention, and inclusion of partners and/or other family members,” the authors said.

In this study, postnatal overweight women with previous GDM were included in a multicentre randomized controlled trial between June 2013 and December 2014. The intervention consisted of a 1-hour educational programme, a free 3-month referral to a commercial weight management organization (Slimming World), a pedometer, and structured telephone and text support, in addition to usual care. The control group received usual care only. Weight loss at 6 months was the main outcome.

“GDM is associated with a sevenfold increased lifetime risk of T2D. Excessive gestational weight gain and postpartum weight retention are established predictors of long-term obesity,” the authors noted.

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Most Read Articles
Roshini Claire Anthony, 28 Jan 2020

Individuals with type 2 diabetes (T2D) who are prescribed an SGLT2* inhibitor may have a reduced risk for developing gout compared with those who are prescribed a GLP-1** receptor agonist, according to a study from the US.

Jairia Dela Cruz, 27 Jan 2020
Bariatric surgery is beneficial to nondiabetic Asian patients with obesity, delivering sustained weight loss in addition to normalizing sugar levels and insulin resistance within 1–3 years of the procedure, as reported in a Singapore study.
5 days ago
Sleep disorder in nonstandard shift workers appears to contribute to more severe hypogonadal symptoms and lower testosterone levels when compared with daytime workers and nonstandard shift workers without sleep disorder, according to a study.