Most Read Articles
01 Oct 2015
BLACKMORES VITAMIN D3 – Vitamin D3 1,000 IU Capsules
15 Dec 2016
New drug applications approved by US FDA as of 1 - 15 December 2016 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.
Kavitha G. Shekar, 21 Jun 2016

The American Diabetes Association’s (ADA) President Desmond Schatz challenged the scientific community to transform diabetes from an invisible disease to a highly visible crisis. “Diabetes is an epidemic spiralling out of control across this country and around the world, yet it remains largely invisible,” he said, speaking at the 76th Scientific Sessions of ADA in New Orleans, Louisiana, US.

31 Jul 2017
New drug applications approved by US FDA as of 16 - 31 July 2017 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.

Postdischarge worsening renal function strongly predicts adverse CV events

11 Sep 2017
Kidney failures and organ donors: Singapore

Postdischarge worsening renal function is common in patients with type 2 diabetes and acute coronary syndromes with normal or mildly depressed renal function, and a strong risk factor for adverse cardiovascular events, according to a recent study.

A total of 204 patients (7.34 percent) had worsening renal function. Over a median follow-up of 2 years, the estimated rates of death and hospital admission for heart failure per 100 person-years were 3.45 (95 percent CI, 2.46 to 6.36) for those with worsening renal function compared with 1.43 (1.14 to 1.79) for patients with stable renal function.

Adjusted analysis revealed that worsening renal function correlated with the composite endpoints of all-cause death and hospitalization for heart failure (hazard ratio, 2.65; 1.57 to 4.49; p<0.001).

In this study, researchers considered the placebo cohort of the AleCardio trial comparing aleglitazar with standard medical therapy among patients with type 2 diabetes mellitus and a recent acute coronary syndrome.

In total, 2,776 patients were included in the analysis. Excluded were those who had died or had been admitted to hospital for heart failure before the 6-month follow-up, as well as patients without complete renal function data.

Worsening renal function was defined as a >20-percent reduction in estimated glomerular filtration rate from discharge to 6 months or progression to macroalbuminuria. Cox regression analysis was used to determine the prognostic impact of 6-month renal deterioration on the composite of all-cause death and hospital admission for heart failure.

“Worsening renal function during hospitalization for an acute coronary syndrome is strongly predictive of in-hospital and long-term outcome,” researchers noted.

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Endocrinology - Malaysia digital copy today!
DOWNLOAD
Editor's Recommendations
Most Read Articles
01 Oct 2015
BLACKMORES VITAMIN D3 – Vitamin D3 1,000 IU Capsules
15 Dec 2016
New drug applications approved by US FDA as of 1 - 15 December 2016 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.
Kavitha G. Shekar, 21 Jun 2016

The American Diabetes Association’s (ADA) President Desmond Schatz challenged the scientific community to transform diabetes from an invisible disease to a highly visible crisis. “Diabetes is an epidemic spiralling out of control across this country and around the world, yet it remains largely invisible,” he said, speaking at the 76th Scientific Sessions of ADA in New Orleans, Louisiana, US.

31 Jul 2017
New drug applications approved by US FDA as of 16 - 31 July 2017 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.