Most Read Articles
Roshini Claire Anthony, 5 days ago

Patients with mild hypertension who are at low risk for cardiovascular disease (CVD) do not appear to derive mortality or CVD benefit from antihypertensive treatments, raising questions on the need for treatment in this population, according to a recent study from England.

Pearl Toh, 09 Nov 2018
A personalized computerized neurofeedback intervention for training attention and memory shows potential in cognitive training for healthy elderly men, who improved in cognitive performance after the training, although no significant improvements were seen in the overall study population.
3 days ago
Type 1 diabetes impairs cognitive functioning in children, and this effect is exacerbated by extreme glycaemic levels, according to a recent meta-analysis.
Pearl Toh, 08 Nov 2018
The pneumonia-causing bacteria, Streptococcus pneumoniae (pneumococcus), can be spread through nose picking and rubbing after exposure of the hands to the bacteria — in addition to the conventionally known route of inhalation of airborne droplets, a study reveals.

Post-treatment symptoms predict depression, anxiety in uveal melanoma survivors

16 Jul 2018

In survivors of uveal melanoma, worry about recurrent disease (WREC) and post-treatment symptoms appear to contribute to long-term anxiety and depression, according to a recent study.

The analysis included 261 uveal melanoma survivors, of whom 26.8 percent (n=70) and 10.1 percent (n=26) had anxiety and depression at 6 months, respectively. The corresponding rates of anxiety and depression at 12 months were 25.7 percent (n=67) and 11.5 percent (n=30). At 24 months, the rates were 22.6 percent (n=59) and 11.5 percent (n=30), respectively.

Ocular irritation (odds ratio [OR], 1.23; 95 percent CI, 1.04–1.45; p<0.05), headaches (OR, 1.77.; 1.07–2.95; p<0.05) and functional problems (OR, 1.12; 1,00–1.25; p<0.05) at 6 months, and WREC at 12 months (OR, 1.34; 1.04–1.73; p<0.05) were significant predictors of anxiety development at 24 months.

In comparison, headaches (OR, 2.32; 1.10–4.92; p<0.05) and functional problems (OR, 1.16; 0.91–1.34; p<0.05) at 6 months were significant predictors of depression at 24 months.

The presence of WREC at 12 months mediated the predictive value for anxiety of the symptoms and functional problems at 6 months. No such predictive effects were observed for chromosome 3 status.

“[T]he focus of attention during follow-up should be on preparing patients to better understand and cope with symptoms and functional problems,” said researchers, noting that patients who report concerns about symptoms and functional problems should be monitored for psychological distress.

In addition, informing patients that symptoms do not necessarily lead to future disease may also help avoid psychological problems.

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Most Read Articles
Roshini Claire Anthony, 5 days ago

Patients with mild hypertension who are at low risk for cardiovascular disease (CVD) do not appear to derive mortality or CVD benefit from antihypertensive treatments, raising questions on the need for treatment in this population, according to a recent study from England.

Pearl Toh, 09 Nov 2018
A personalized computerized neurofeedback intervention for training attention and memory shows potential in cognitive training for healthy elderly men, who improved in cognitive performance after the training, although no significant improvements were seen in the overall study population.
3 days ago
Type 1 diabetes impairs cognitive functioning in children, and this effect is exacerbated by extreme glycaemic levels, according to a recent meta-analysis.
Pearl Toh, 08 Nov 2018
The pneumonia-causing bacteria, Streptococcus pneumoniae (pneumococcus), can be spread through nose picking and rubbing after exposure of the hands to the bacteria — in addition to the conventionally known route of inhalation of airborne droplets, a study reveals.