Most Read Articles
Roshini Claire Anthony, 4 days ago

The presence of pulmonary arterial hypertension (PAH) in individuals with systemic sclerosis is associated with an increased mortality risk, a study from Singapore showed.

23 Dec 2019
At a Menarini-sponsored symposium held during the Asian Pacific Society Congress, renowned cardiologist Prof John Camm provided the latest evidence for chronic stable angina with or without concomitant diseases, with a special focus on the antianginal agent ranolazine and combination therapies. The event was chaired and moderated by Dr Dante Morales from the University of the Philippines College of Medicine.
3 days ago
Serum 25-hydroxyvitamin D (25[OH]D) levels are significantly lower among patients with active uveitis than those with inactive uveitis and local population-based estimates, reports a study. In addition, vitamin D supplementation may help reduce uveitis activity, while sun exposure confers a beneficial effect to those with vitamin D deficiency.
2 days ago
The timing of direct oral anticoagulants (DOACs) administration, either within 3 days or ≥4 days of stroke onset, in patients with nonvalvular atrial fibrillation (AF) does not alter the risk of adverse outcomes such as stroke or systemic embolism, major bleeding, and death, as shown in a recent study.

Poor sleep intensifies pain, fatigue among osteoarthritis patients

11 Nov 2019

Better sleep appears to weaken pain and fatigue in older, community-dwelling adults with hip or knee osteoarthritis (OA), reports a recent study. 

The study included 160 community-dwelling elderly adults (median age, 71 years; 61.9 percent female) who provided sleep data using daily diaries and actigraphy; subjective sleep quality was assessed upon waking up. OA pain intensity and fatigue were evaluated at 11 AM, 3 PM, 7 PM and at bedtime.  

The median sleep efficiency was 7.35 hours, with a median efficiency of 83.8 percent. Participants reported a median sleep latency of 16 minutes and a wake time after sleep onset of 42 minutes. Self-reported sleep quality was fair.

Across an average day, fatigue intensity scores ranged from 3.27 to 4.97, while pain scores ranged from 3.04 to 3.39. However, clear diurnal patterns were observed.

Multilevel linear regression models found that sleep quality was significantly correlated with the time of next-day pain report (p<0.001). Specifically, better sleep quality attenuated pain intensity upon waking, but not at any other time point during the day.

The same was true for next-day fatigue, which was likewise significantly associated with sleep quality (p<0.001). Better sleep the night before led to lower fatigue upon waking up. The difference in relation to sleep quality was progressively attenuated at each subsequent time point.

“If supported by further research, people living with OA may be counselled about the likely outcome of a poor night’s sleep on their symptoms, and this information may be used to inform the optimal timing of pharmacologic and/or nonpharmacologic interventions,” said researchers.

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Most Read Articles
Roshini Claire Anthony, 4 days ago

The presence of pulmonary arterial hypertension (PAH) in individuals with systemic sclerosis is associated with an increased mortality risk, a study from Singapore showed.

23 Dec 2019
At a Menarini-sponsored symposium held during the Asian Pacific Society Congress, renowned cardiologist Prof John Camm provided the latest evidence for chronic stable angina with or without concomitant diseases, with a special focus on the antianginal agent ranolazine and combination therapies. The event was chaired and moderated by Dr Dante Morales from the University of the Philippines College of Medicine.
3 days ago
Serum 25-hydroxyvitamin D (25[OH]D) levels are significantly lower among patients with active uveitis than those with inactive uveitis and local population-based estimates, reports a study. In addition, vitamin D supplementation may help reduce uveitis activity, while sun exposure confers a beneficial effect to those with vitamin D deficiency.
2 days ago
The timing of direct oral anticoagulants (DOACs) administration, either within 3 days or ≥4 days of stroke onset, in patients with nonvalvular atrial fibrillation (AF) does not alter the risk of adverse outcomes such as stroke or systemic embolism, major bleeding, and death, as shown in a recent study.