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Roshini Claire Anthony, 11 Sep 2019

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Poor sleep contributes to worse LUTS in nonstandard shift workers

08 Jun 2019

Men working shifts outside of a normal 7 am to 6 pm work day who are at high risk of shift work disorder (SWD) appear to have worse lower urinary tract symptoms (LUTS) than their counterparts who are at low SWD risk, a study reports. However, nonstandard shift work in general is not associated with LUTS.

SWD was defined as insomnia or excessive sleepiness, accompanied by reduced total sleep time due to work schedule, with symptoms present and associated with shift work for at least 3 months that lead to significant distress or impairment in mental, physical, social or other areas of functioning.

In the study, 2,571 men who presented to a single andrology clinic completed questionnaires regarding work schedules, shift work status, SWD, personal well-being and LUTS (International Prostate Symptom Score [IPSS]). None of the participants had previously undergone prostate surgery.

A total of 619 men (24.1 percent) reported working nonstandard shifts in the past month, among whom 196 (31.7 percent) had high SWD risk.

Linear regression models adjusted for age, medications, surgical intervention for benign prostatic hyperplasia, comorbidities and testosterone levels showed no association between nonstandard shift work overall and worse LUTS (p=0.82).

On the other hand, nonstandard shift workers at high risk of SWD had significantly higher IPSS scores than nonstandard shift workers without SWD (difference, 3.74 points; p<0.0001).

When assessing sleep factors, worse LUTS correlated with poor sleep quality and increased difficulty staying asleep, and increased difficulty falling asleep, waking up too early and being unable to fall back asleep. These suggest that sleep quality plays an important role in the relationship between SWD and LUTS, as pointed out by researchers.

Meanwhile, sleep quality and shift work have been implicated in metabolic syndrome, which has been associated with prostatic inflammation and higher IPSS scores, they added.

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Most Read Articles
Roshini Claire Anthony, 11 Sep 2019

Beta-blockers could reduce mortality risk in patients with heart failure with reduced ejection fraction (HFrEF) and moderate or moderately-severe renal dysfunction without causing harm, according to the BB-META-HF* trial presented at ESC 2019.

Elvira Manzano, 2 days ago

The US Preventive Services Task Force (USPSTF), in an update of its 2013 recommendations, called on clinicians to offer risk-reducing medications to women who are at increased risk for breast cancer but at low risk for adverse effects.

Pearl Toh, 3 days ago
The use of SGLT-2* inhibitors was not associated with a higher risk of severe or nonsevere urinary tract infections (UTIs) in patients with type 2 diabetes (T2D) compared with DPP**-4 inhibitors or GLP-1*** receptor agonists, a population-based cohort study shows.
6 days ago
In type 2 diabetes patients taking sulfonylureas, hypoglycaemia duration is longer at night and is inversely correlated with the level of glycated haemoglobin (HbA1c), a new study reports.