Poor sleep contributes to worse LUTS in nonstandard shift workers
Men working shifts outside of a normal 7 am to 6 pm work day who are at high risk of shift work disorder (SWD) appear to have worse lower urinary tract symptoms (LUTS) than their counterparts who are at low SWD risk, a study reports. However, nonstandard shift work in general is not associated with LUTS.
SWD was defined as insomnia or excessive sleepiness, accompanied by reduced total sleep time due to work schedule, with symptoms present and associated with shift work for at least 3 months that lead to significant distress or impairment in mental, physical, social or other areas of functioning.
In the study, 2,571 men who presented to a single andrology clinic completed questionnaires regarding work schedules, shift work status, SWD, personal well-being and LUTS (International Prostate Symptom Score [IPSS]). None of the participants had previously undergone prostate surgery.
A total of 619 men (24.1 percent) reported working nonstandard shifts in the past month, among whom 196 (31.7 percent) had high SWD risk.
Linear regression models adjusted for age, medications, surgical intervention for benign prostatic hyperplasia, comorbidities and testosterone levels showed no association between nonstandard shift work overall and worse LUTS (p=0.82).
On the other hand, nonstandard shift workers at high risk of SWD had significantly higher IPSS scores than nonstandard shift workers without SWD (difference, 3.74 points; p<0.0001).
When assessing sleep factors, worse LUTS correlated with poor sleep quality and increased difficulty staying asleep, and increased difficulty falling asleep, waking up too early and being unable to fall back asleep. These suggest that sleep quality plays an important role in the relationship between SWD and LUTS, as pointed out by researchers.
Meanwhile, sleep quality and shift work have been implicated in metabolic syndrome, which has been associated with prostatic inflammation and higher IPSS scores, they added.