Most Read Articles
Yesterday
In patients with rheumatoid arthritis (RA) who are also positive for anticitrullinated protein antibodies (ACPA), tocilizumab (TCZ) treatment for 2 years increases femoral neck bone mineral density (BMD) and decreases concentrations of bone resorption markers, a recent study has found.
3 days ago
Long-term use of benzodiazepines is independently associated with lower diastolic and systolic blood pressure in ambulatory blood pressure monitoring (ABPM) among older but not younger patients, a study has found.
5 days ago
There appears to be a paradox in the context of smoking and the risk of psoriatic arthritis (PsA), such that current smoking increases the risk of developing PsA in the general population but protects against the same risk among patients with psoriasis, according to a study.
02 Nov 2017
In this issue of MIMS Anti-Infective Supplement, we bring you clinical updates related to combating infectious diseases, and also a symposium highlight in conjunction with the launch of ceftolozane/tazobactam (Zerbaxa; Merck Sharp & Dohme Sdn Bhd) in Malaysia. 

Physical activity may promote cognitive recovery poststroke

13 Nov 2017

Physical activity (PA) training appears to positively affect cognition in stroke survivors, with small to moderate gains achieved even if introduced in the chronic stroke phase, a study has found.

Researchers performed a systematic review and meta-analysis of trials investigating the relationship between structured PA training and cognitive performance after stroke. Intervention effects, represented as Hedges’ g, were combined using random- and mixed-effects models. Effect sizes were then subjected to moderation analyses using the between-group heterogeneity test.

Pooled data from 14 studies, which involved 736 participants, showed that PA had a positive overall effect on cognitive performance (Hedges’ g, 0.304; 95 percent CI, 0.14 to 0.47).

Cognitive benefits were achieved as early as 12 weeks of PA training. The largest cognitive gains were seen with combined aerobic and strength training programmes, which also yielded improvements in cognitive performance even in the chronic stroke phase (mean, 2.6 years poststroke).

In particular, there were positive moderate treatment effects found for attention/processing speed measures (Hedges’ g, 0.37; 0.10 to 0.63), while those observed for executive function and working memory domains did not reach significance (p>0.05).

The present data indicate that PA training may reduce the burden of cognitive deficits in stroke survivors, researchers said.

Additionally, the study underscores several critical avenues for future work, such as identifying the ideal window of time after a stroke and the optimal training parameters needed to maximize cognitive recovery, they added.

Researchers recommended including participants with more severe levels of cognitive and physical impairment in future trials to enhance generalizability, as well as to help inform and tailor PA according to the needs and abilities of these patients.

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Doctor - Malaysia digital copy today!
DOWNLOAD
Editor's Recommendations
Most Read Articles
Yesterday
In patients with rheumatoid arthritis (RA) who are also positive for anticitrullinated protein antibodies (ACPA), tocilizumab (TCZ) treatment for 2 years increases femoral neck bone mineral density (BMD) and decreases concentrations of bone resorption markers, a recent study has found.
3 days ago
Long-term use of benzodiazepines is independently associated with lower diastolic and systolic blood pressure in ambulatory blood pressure monitoring (ABPM) among older but not younger patients, a study has found.
5 days ago
There appears to be a paradox in the context of smoking and the risk of psoriatic arthritis (PsA), such that current smoking increases the risk of developing PsA in the general population but protects against the same risk among patients with psoriasis, according to a study.
02 Nov 2017
In this issue of MIMS Anti-Infective Supplement, we bring you clinical updates related to combating infectious diseases, and also a symposium highlight in conjunction with the launch of ceftolozane/tazobactam (Zerbaxa; Merck Sharp & Dohme Sdn Bhd) in Malaysia.