Most Read Articles
3 days ago
The appropriate cutoff value in predicting combined cardiovascular outcomes in patients with type 2 diabetes (T2D) is 125 mm Hg for home morning systolic blood pressure (MSBP), suggests a new study.
06 Apr 2018

Female patients with coronary artery disease (CAD) have greater regression of coronary atherosclerosis than male patients despite a lower plaque burden at baseline, data from the GLAGOV trial have shown.

26 Apr 2018
Transcatheter aortic valve replacement (TAVR) in severe symptomatic aortic stenosis (AS) patients is superior to conventional surgical aortic valve replacement (SAVR) in terms of reducing life-threatening bleeding, new-onset atrial fibrillation and acute kidney injury, a recent meta-analysis has found.
Pearl Toh, Yesterday
Whether the 2017 ACC/AHA* blood pressure (BP) guidelines should be adopted in Asian countries was the topic of a much-anticipated discussion here at the Asian Pacific Society of Cardiology (APSC) Congress 2018 in Taiwan last week.

Peripheral, not central, BP correlates better with hypertensive target organ damage

18 Sep 2017

The presence of target organ damage (TOD) in hypertension is more likely to result in blood pressure (BP) elevation, independently of the type of measurement (office or ambulatory, central or peripheral), according to a recent study. Central BP, even monitored during 24 hours, is not better correlated with TOD than peripheral BP.

Researchers performed a cross-sectional study of 208 hypertensive patients (mean age 57±12 years; 34 percent women) to examine the association of 24-hour central BP, in comparison with 24-hour peripheral BP, with the presence of TOD.

The oscillometric Mobil-O-Graph device was used to measure office (mean of four measurements) and 24-hour central and peripheral BP. The investigators assessed TOD at cardiac (left ventricular hypertrophy by echocardiography), renal (reduction of glomerular filtration rate and/or microalbuminuria) and arterial (increased aortic pulse wave velocity) levels.

Of the patients, 107 (51.4 percent) had TOD (77 [35 percent] left ventricular hypertrophy; 54 [25.9 percent] renal abnormalities; 40 [19.2 percent] arterial stiffness).

After adjustment for age, sex and antihypertensive treatment, all systolic (S)BP and pulse BP estimates (office, 24-hour, daytime and night-time) correlated with the presence of TOD, with higher odds ratios (ORs) for ambulatory-derived values.

There were similar ORs for central and peripheral BP for all office, 24-hour, daytime and night-time BP. After simultaneous adjustment, peripheral, but not central, 24-hour and night-time SBP and pulse pressures correlated with the presence of TOD.

These findings do not lend support to a routine measurement of 24-hour central BP, which is increasingly considered as a better estimator of hypertension-associated risks, according to researchers.

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Most Read Articles
3 days ago
The appropriate cutoff value in predicting combined cardiovascular outcomes in patients with type 2 diabetes (T2D) is 125 mm Hg for home morning systolic blood pressure (MSBP), suggests a new study.
06 Apr 2018

Female patients with coronary artery disease (CAD) have greater regression of coronary atherosclerosis than male patients despite a lower plaque burden at baseline, data from the GLAGOV trial have shown.

26 Apr 2018
Transcatheter aortic valve replacement (TAVR) in severe symptomatic aortic stenosis (AS) patients is superior to conventional surgical aortic valve replacement (SAVR) in terms of reducing life-threatening bleeding, new-onset atrial fibrillation and acute kidney injury, a recent meta-analysis has found.
Pearl Toh, Yesterday
Whether the 2017 ACC/AHA* blood pressure (BP) guidelines should be adopted in Asian countries was the topic of a much-anticipated discussion here at the Asian Pacific Society of Cardiology (APSC) Congress 2018 in Taiwan last week.