Most Read Articles
Stephen Padilla, 05 Jan 2018
The addition of an antihypertensive drug from a new class to a patient’s regimen results in huge decreases in systolic blood pressure (SBP) and major cardiovascular (CV) events among those at high risk for CV events but without diabetes, suggests a recent study. Its effects on SBP remain large and similar in magnitude across all levels of baseline drug use and all subgroups of patients.
Pearl Toh, 3 days ago
A study finds no evidence that using pharmaceutical aids alone for smoking cessation helps improve the chances of successful quitting despite promising results in previous randomized trials and routine prescription of such drugs to help quit smoking.
04 Jan 2018
Thromboembolism is a major cause of death in patients with cancer, which is why clinicians should check for the symptoms of thromboembolic events right from the initial stages of bevacizumab treatment, suggests a recent study.
04 Jan 2018
Statins appear to reduce the severity of acute pancreatitis (AP), as demonstrated by a decrease in overall incidence of multisystem organ failure (MSOF), according to a study.

Periodontitis tied to nonalcoholic fatty liver disease

17 Dec 2017

Periodontitis is associated with nonalcoholic fatty liver disease (NAFLD), a recent epidemiological study has shown, adding that the presence of significant liver fibrosis makes this association more robust.

In the first part of the study, where researchers retrieved data from a population-based survey, findings showed that antibodies to the bacterial species Streptococcus noxia and S. oralis were strongly associated with the presence of steatosis even after adjusting for metabolic syndrome (odds ratios, 1.13 and 1.14, respectively).

Moreover, periodontal disease was found to be more severe in patients with advanced NAFLD, with those having high-risk NAFLD fibrosis scores (NFS) presenting with more clinical attachment loss (CAL) than those with low-risk scores.

In a subsequent patient-based study, where 69 NAFLD patients underwent dental examination, researchers found 12 periodontitis cases, resulting in a prevalence rate of 17.4 percent. Diabetes was significantly more frequent in the periodontitis patients (p=0.021).

Periodontitis patients were also significantly more likely to have nonalcoholic steatohepatitis (NASH) of any stage (p=0.0085) and NASH with fibrosis stages F2 to 4 (p=0.005) than those without periodontitis.

Periodontitis was also significantly associated with the stage of liver disease (NASH vs NFLD, p=0.008) and diabetes (p=0.01). Anthropometric and demographic factors such as age, body mass index, waist circumference, blood pressure, ethnicity, sex, and smoking status were unrelated to periodontitis.

“Epidemiological and clinical data reported here independently show a link between periodontitis and NAFLD, and this link is explained by features of metabolic syndrome including diabetes,” said researchers.

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Most Read Articles
Stephen Padilla, 05 Jan 2018
The addition of an antihypertensive drug from a new class to a patient’s regimen results in huge decreases in systolic blood pressure (SBP) and major cardiovascular (CV) events among those at high risk for CV events but without diabetes, suggests a recent study. Its effects on SBP remain large and similar in magnitude across all levels of baseline drug use and all subgroups of patients.
Pearl Toh, 3 days ago
A study finds no evidence that using pharmaceutical aids alone for smoking cessation helps improve the chances of successful quitting despite promising results in previous randomized trials and routine prescription of such drugs to help quit smoking.
04 Jan 2018
Thromboembolism is a major cause of death in patients with cancer, which is why clinicians should check for the symptoms of thromboembolic events right from the initial stages of bevacizumab treatment, suggests a recent study.
04 Jan 2018
Statins appear to reduce the severity of acute pancreatitis (AP), as demonstrated by a decrease in overall incidence of multisystem organ failure (MSOF), according to a study.