Most Read Articles
01 Mar 2016
Combination therapy with ezetimibe/statin improved low-density lipoprotein (LDL) cholesterol levels and cardiovascular outcomes in patients with acute coronary syndrome (ACS), as stated in a 16-week one-centre, prospective, randomised, open-label clinical trial.
13 Aug 2016
Prasugrel is superior than clopidogrel in the treatment of acute coronary syndrome (ACS) and ST-elevation myocardial infarction (STEMI) patients undergoing primary percutaneous coronary intervention (PCI) as presented in a study.
01 Mar 2016
Earlier oral β blocker administration is substantially correlated with lower rates of left ventricular (LV) dysfunction and in-hospital mortality in acute coronary syndrome patients, according to a study.
16 Dec 2018
The absence of the classical symptom of chest pain in patients with acute myocardial infarction (AMI) appears to be associated with more complications and higher short- and long-term mortality rates, particularly in younger and healthier patients, according to a study.

PCI safe for obese patients, but may introduce increasing radiation doses

12 Jun 2018

Percutaneous coronary intervention (PCI) is a safe procedure to perform on obese and morbidly obese patients, a recent study has shown.

Researchers accessed the medical records of 1,082 patients who underwent PCI, of whom 688 were nonobese (NO; body mass index [BMI] <30; median age 67 years; 75.6 percent male), 354 were obese (O; median age 65.5 years; 75.4 percent male) and 40 were morbidly obese (MO; median age 62.5 years; 57.5 percent male).

Study outcomes included in-hospital major adverse cardiovascular or cerebrovascular events (MACCE), acute kidney injury (AKI) and bleeding events.

Relative to NO patients, O and MO patients showed the same incidence rates of MACCE (1.2 percent vs 0.8 percent vs 2.5 percent), AKI (1.6 percent vs 1.1 percent vs 0.0 percent), any bleeding (16.1 percent vs 13.3 percent vs 15.4 percent) and major bleeding events (0.8 percent vs 0.8 percent vs 0.0 percent).

On the other hand, contrast usage was higher in O and MO than NO patients (190 vs 200 vs 180 mL; p=0.016), as was the median fluoroscopic dose area product (DAP; 116.4 vs 125.62 vs 75.56 Gycm2; p=0.0001) and median entrance air kerma (EAK; 2,111.63 vs 2,376.0 vs 1,439.42 mGy; p=0.0001).

Multiple linear and regression analyses showed that increasing contrast usage, fluoroscopic DAP and EAK remained significantly correlated with increasing BMI (p<0.0001 for all).

“With increasing obesity, patients undergoing PCI are exposed to increasing doses of radiation. This increases the risk of skin effects for both obese and morbidly obese patients and increases the risk of late effects of radiation in obese patients,” said researchers.

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Cardiology - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
01 Mar 2016
Combination therapy with ezetimibe/statin improved low-density lipoprotein (LDL) cholesterol levels and cardiovascular outcomes in patients with acute coronary syndrome (ACS), as stated in a 16-week one-centre, prospective, randomised, open-label clinical trial.
13 Aug 2016
Prasugrel is superior than clopidogrel in the treatment of acute coronary syndrome (ACS) and ST-elevation myocardial infarction (STEMI) patients undergoing primary percutaneous coronary intervention (PCI) as presented in a study.
01 Mar 2016
Earlier oral β blocker administration is substantially correlated with lower rates of left ventricular (LV) dysfunction and in-hospital mortality in acute coronary syndrome patients, according to a study.
16 Dec 2018
The absence of the classical symptom of chest pain in patients with acute myocardial infarction (AMI) appears to be associated with more complications and higher short- and long-term mortality rates, particularly in younger and healthier patients, according to a study.