Most Read Articles
11 Dec 2017
Combining the DASH (Dietary Approaches to Stop Hypertension) diet with low sodium intake reduces systolic blood pressure (SBP) in individuals with pre- and stage 1 hypertension, with progressively higher reductions at greater levels of baseline SBP, a recent study has shown.
Tristan Manalac, 5 days ago
Major depressive disorder (MDD) appears to be more prevalent in females than in males, particularly in those who are divorced or widowed, a recent study from Singapore has found.
6 days ago
Tadalafil may not be effective for reducing the decline in ambulatory ability in boys with Duchenne muscular dystrophy (DMD), as shown in a recent study.
01 Dec 2017
At a symposium during the 25th Congress of the Obstetrical and Gynaecological Society of Malaysia in Kuala Lumpur, Professor Susan Davis discussed the unique implications of women living decades beyond menopause, and how healthcare professionals can best manage menopausal symptoms in the short and long term.

Patients with psoriatic disease have poor sleep quality

27 Sep 2017
Many studies have investigated various risk factors that can contribute to snoring as well as its effects.

Poor sleep quality is not uncommon among patients with psoriatic disease, suggests a recent study. Poor sleep is associated with fatigue, anxiety and lower EQ-5D. It is also associated with actively inflamed joints in patients with psoriatic arthritis (PsA).

A total of 113 PsA and 62 psoriasis without PsA (PsC) patients, as well as 52 healthy controls, were included in this study. Researchers collected clinical variables using a standard protocol. The Pittsburgh Sleep Quality Index (PSQI) was used to evaluated sleep quality.

The investigators also collected other patient-reported outcomes such as the Health Assessment Questionnaire, Dermatology Life Quality Index, EQ-5D, Medical Outcomes Study Short Form-36 survey, patient’s global assessment and the Functional Assessment of Chronic Illness Therapy (FACIT)-Fatigue scale. Descriptive statistics, Wilcoxon rank-sum test and linear regression were included in the statistical analyses.

The prevalence of poor sleep quality was 84 percent in PsA, 69 percent in PsC and 50 percent in healthy controls. Total PSQI score was higher in both PsA and PsC patients compared with healthy controls (p<0.01). Furthermore, PsA patients had higher PSQI score than PsC patients (p<0.0001).

EQ-5D anxiety component, EQ-5D final and FACIT-fatigue were independently associated with worse PSQI in both PsA and PsC patients (p<0.05). Active joint inflammations (tender or swollen) independently correlated with worse PSQI in patients with PsA (p<0.01).

These results support those in the study by Gezer and colleagues, who found that sleep quality is diminished in patients with PsA. Particularly, sleep disturbance correlated with generalized pain, anxiety and enthesitis, among others, in PsA patients. [Int J Rheum Dis 2014;doi:10.1111/1756-185X]

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Most Read Articles
11 Dec 2017
Combining the DASH (Dietary Approaches to Stop Hypertension) diet with low sodium intake reduces systolic blood pressure (SBP) in individuals with pre- and stage 1 hypertension, with progressively higher reductions at greater levels of baseline SBP, a recent study has shown.
Tristan Manalac, 5 days ago
Major depressive disorder (MDD) appears to be more prevalent in females than in males, particularly in those who are divorced or widowed, a recent study from Singapore has found.
6 days ago
Tadalafil may not be effective for reducing the decline in ambulatory ability in boys with Duchenne muscular dystrophy (DMD), as shown in a recent study.
01 Dec 2017
At a symposium during the 25th Congress of the Obstetrical and Gynaecological Society of Malaysia in Kuala Lumpur, Professor Susan Davis discussed the unique implications of women living decades beyond menopause, and how healthcare professionals can best manage menopausal symptoms in the short and long term.