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Patients with hidradenitis suppurativa at higher risk of substance use disorder

07 Sep 2018
Substance abuse among the elderly is dangerous and require special attention to address the underlying problems.

Hidradenitis suppurativa (HS) is associated with an increased risk of substance use disorder (SUD), according to a US study. Patients with HS may benefit from periodic screening for substance abuse.

SUD prevalence among patients with HS was 4.0 percent (1,315/32,625) vs 2.0 percent (195,260/9,581,640) for those without HS (p<0.001). The most common forms of substance misuse among HS patients were as follows: alcohol (47.9 percent), opioids (32.7 percent) and cannabis (29.7 percent).

Patients with vs without HS had 1.50 (95 percent CI, 1.42–1.59) times the adjusted odds of SUD. The association between HS and SUD was generally stronger among the following: patients aged 45–64 years, nonwhites, privately insured, and those without depressive or anxiety disorder.

An earlier study found that patients at higher risk for prescription opioid misuse among those with SUD histories reported more pain and impairment, symptoms of depression, and were more likely to have current SUD compared to those at lower risk for misuse. Adjusted analysis showed pain catastrophizing to be significantly associated with risk for prescription opioid misuse. [Drug Alcohol Depend 2013;127:193-199]

In the present cross-sectional analysis that assessed SUD among HS patients in the US, the authors identified adult HS patients (n=32,625) using electronic health records data drawn from a population-based sample of >50 million patients.

One limitation of the study was that SUD might not have been accurately diagnosed, the authors said.

“Patients with HS experience chronic pain and have significant physical, emotional and psychological disease impact. These patients may be at risk for substance abuse,” they noted.

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Most Read Articles
Tristan Manalac, 01 Mar 2019
Poor diet quality appears to impair mental health, according to a new study.
05 Mar 2019
Obesity and allergic disease increase the risk of mental health problems in adolescents, a recent Korea study has found.
Tristan Manalac, 15 Mar 2019
Neither multinutrient supplementation nor food-related behavioural activation therapy appear to protect against major depressive disorder (MDD) episodes in overweight or obese adults with subsyndromal depressive symptoms, according to a recent study.
11 Apr 2019
Cannabis use disorder appears to exert a beneficial effect on the risk of disorders of gut–brain interaction and inflammatory bowel disease in patients with schizophrenia but not in population controls, a study has found. This finding raises the possibility of new targets for treatment and prevention of digestive organ disorders in schizophrenia.