Most Read Articles
Roshini Claire Anthony, 11 Sep 2019

Beta-blockers could reduce mortality risk in patients with heart failure with reduced ejection fraction (HFrEF) and moderate or moderately-severe renal dysfunction without causing harm, according to the BB-META-HF* trial presented at ESC 2019.

Elvira Manzano, 2 days ago

The US Preventive Services Task Force (USPSTF), in an update of its 2013 recommendations, called on clinicians to offer risk-reducing medications to women who are at increased risk for breast cancer but at low risk for adverse effects.

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The use of SGLT-2* inhibitors was not associated with a higher risk of severe or nonsevere urinary tract infections (UTIs) in patients with type 2 diabetes (T2D) compared with DPP**-4 inhibitors or GLP-1*** receptor agonists, a population-based cohort study shows.
6 days ago
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Patients with hidradenitis suppurativa at higher risk of substance use disorder

07 Sep 2018
Substance abuse among the elderly is dangerous and require special attention to address the underlying problems.

Hidradenitis suppurativa (HS) is associated with an increased risk of substance use disorder (SUD), according to a US study. Patients with HS may benefit from periodic screening for substance abuse.

SUD prevalence among patients with HS was 4.0 percent (1,315/32,625) vs 2.0 percent (195,260/9,581,640) for those without HS (p<0.001). The most common forms of substance misuse among HS patients were as follows: alcohol (47.9 percent), opioids (32.7 percent) and cannabis (29.7 percent).

Patients with vs without HS had 1.50 (95 percent CI, 1.42–1.59) times the adjusted odds of SUD. The association between HS and SUD was generally stronger among the following: patients aged 45–64 years, nonwhites, privately insured, and those without depressive or anxiety disorder.

An earlier study found that patients at higher risk for prescription opioid misuse among those with SUD histories reported more pain and impairment, symptoms of depression, and were more likely to have current SUD compared to those at lower risk for misuse. Adjusted analysis showed pain catastrophizing to be significantly associated with risk for prescription opioid misuse. [Drug Alcohol Depend 2013;127:193-199]

In the present cross-sectional analysis that assessed SUD among HS patients in the US, the authors identified adult HS patients (n=32,625) using electronic health records data drawn from a population-based sample of >50 million patients.

One limitation of the study was that SUD might not have been accurately diagnosed, the authors said.

“Patients with HS experience chronic pain and have significant physical, emotional and psychological disease impact. These patients may be at risk for substance abuse,” they noted.

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Most Read Articles
Roshini Claire Anthony, 11 Sep 2019

Beta-blockers could reduce mortality risk in patients with heart failure with reduced ejection fraction (HFrEF) and moderate or moderately-severe renal dysfunction without causing harm, according to the BB-META-HF* trial presented at ESC 2019.

Elvira Manzano, 2 days ago

The US Preventive Services Task Force (USPSTF), in an update of its 2013 recommendations, called on clinicians to offer risk-reducing medications to women who are at increased risk for breast cancer but at low risk for adverse effects.

Pearl Toh, 3 days ago
The use of SGLT-2* inhibitors was not associated with a higher risk of severe or nonsevere urinary tract infections (UTIs) in patients with type 2 diabetes (T2D) compared with DPP**-4 inhibitors or GLP-1*** receptor agonists, a population-based cohort study shows.
6 days ago
In type 2 diabetes patients taking sulfonylureas, hypoglycaemia duration is longer at night and is inversely correlated with the level of glycated haemoglobin (HbA1c), a new study reports.