Patch measures cortisol in sweat

Dr. Joseph Delano Fule Robles
10 Oct 2018
Patch measures cortisol in sweat
Cortisol sensor applied to volunteer’s forearm. Photo from Sci Adv 2018;4:eaar2904.
 A nanoporous membrane-based wearable sensor has been invented for noninvasive detection of cortisol levels in sweat. 

The device, invented by material scientists from Stanford University, California, US, is composed of a wearable sweat diagnostics platform made up of a synthetic and biomimetic polymeric membrane integrated with an electrochemical transistor. The membrane provides accurate sweat acquisition and measurement of the human stress hormone cortisol. [Sci Adv 2018;4:eaar2904]

“We are interested in sweat sensing as it is noninvasive and can provide continuous monitoring of various biomarkers,” said investigator Dr Onur Parlak.

The wearable device was tested by application to a volunteer’s forearm to assess cortisol concentration after a 20-minute intensive outdoor running exercise, and was validated by cortisol level quantification using enzyme linked immunosorbent (ELISA) assays.

Initial results suggested that the design principles of this wearable sensor can be adapted for the detection of various other biomolecules and hormones.

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