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Patch measures cortisol in sweat

Dr. Joseph Delano Fule Robles
10 Oct 2018
Cortisol sensor applied to volunteer’s forearm. Photo from Sci Adv 2018;4:eaar2904.
 A nanoporous membrane-based wearable sensor has been invented for noninvasive detection of cortisol levels in sweat. 

The device, invented by material scientists from Stanford University, California, US, is composed of a wearable sweat diagnostics platform made up of a synthetic and biomimetic polymeric membrane integrated with an electrochemical transistor. The membrane provides accurate sweat acquisition and measurement of the human stress hormone cortisol. [Sci Adv 2018;4:eaar2904]

“We are interested in sweat sensing as it is noninvasive and can provide continuous monitoring of various biomarkers,” said investigator Dr Onur Parlak.

The wearable device was tested by application to a volunteer’s forearm to assess cortisol concentration after a 20-minute intensive outdoor running exercise, and was validated by cortisol level quantification using enzyme linked immunosorbent (ELISA) assays.

Initial results suggested that the design principles of this wearable sensor can be adapted for the detection of various other biomolecules and hormones.

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Most Read Articles
Jairia Dela Cruz, 05 Oct 2020
Drinking more than two cups of coffee per day may just be the intervention that prevents hundreds of thousands of liver disease‐related deaths globally, a study reports.
Pearl Toh, 21 Sep 2020
Early and sustained treatments with simplified regimen are the key to achieving good asthma control, said experts during a presentation at the ERS 2020 Congress.
Roshini Claire Anthony, 12 Oct 2020

Insulin icodec, an in-development basal insulin analogue administered once weekly, was as effective as once-daily insulin glargine in patients with type 2 diabetes (T2D) insufficiently controlled with metformin with or without a DPP-4* inhibitor, according to a phase II trial presented at EASD 2020.

Stephen Padilla, Yesterday
Use of systemic corticosteroids does not reduce in-hospital mortality for patients with severe or critical coronavirus disease (COVID-19), which is in stark contrast to that observed in the RECOVERY clinical trial, according to a study in Wuhan, China.