Most Read Articles
18 May 2020
Immobilization or disuse of the forearm leads to impairment in the ability of a protein-rich meal to promote positive muscle amino acid balance, which is aggravated by dietary lipid oversupply, suggests a study. Disuse also lowers postprandial forearm amino acid uptake, but this is not exacerbated under high-fat conditions.
18 May 2020
Glucagon-like peptide-1 receptor agonists (GLP-1RA) are more effective than basal insulin in the management of total (TC) and low-density lipoprotein cholesterol (LDL-C), reveals a recent study.
17 May 2020
Increased coffee consumption among regular drinkers is associated with higher estimated glomerular filtration rate and confers protection against the risk of chronic kidney disease stages G3–G5 and albuminuria, as shown in a study.
Jairia Dela Cruz, 16 May 2020
Excess weight, greater abdominal fat, inflammation and low physical performance can all contribute to insulin resistance in middle-age Singaporean women, and these variables explain why the condition is more common among women of Chinese than Malay and Indian ethnicities, a study has found.

Parameters of anxiety in children with cancer vary according to instrument used

06 Feb 2019

The severity, patterns over time and predictors of anxiety in children and adolescents undergoing chemotherapy or haematopoietic stem cell transplantation (HSCT) change with different instruments used, a new study has found.

Seventy-seven paediatric patients (median age 13.2 years; 35.1 percent female) participated, in whom self-reported anxiety at chemotherapy or HSCT initiation was measured using three instruments: the Paediatric Quality of Life Inventory (PedsQL) 3.0 Acute Cancer Module, the Paediatric Patient-Reported Outcomes Measurement Information System (PROMIS) Paediatric Short-Form (SF) and the Multidimensional Anxiety Scale for Children (MASC).

At baseline, the percentage of participants who had severe anxiety ranged from 13.0–28.6 percent and varied according to the instrument used. When the PedsQL (procedural anxiety subscale: p=0.037) and PROMIS (p=0.013) instruments were used, significant improvements in anxiety were observed. No such change was recorded by the MASC.

There also seemed to be a variation among instruments regarding predictive factors. Univariate linear regression analysis showed that in the PedsQL instrument, age was a significant risk factor for anxiety, such that children aged 16–18 years reported more worries than those aged 8–11 years (p=0.036).

In comparison, the MASC instrument reported that lower annual household income was also a significant risk factor for anxiety in the participants (p=0.028).

The present findings highlight the heterogeneous nature of childhood anxiety and the need for careful consideration when choosing a measurement instrument, said researchers. Future studies about anxiety in paediatric cancer should focus on a particular facet of anxiety.

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Doctor - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
18 May 2020
Immobilization or disuse of the forearm leads to impairment in the ability of a protein-rich meal to promote positive muscle amino acid balance, which is aggravated by dietary lipid oversupply, suggests a study. Disuse also lowers postprandial forearm amino acid uptake, but this is not exacerbated under high-fat conditions.
18 May 2020
Glucagon-like peptide-1 receptor agonists (GLP-1RA) are more effective than basal insulin in the management of total (TC) and low-density lipoprotein cholesterol (LDL-C), reveals a recent study.
17 May 2020
Increased coffee consumption among regular drinkers is associated with higher estimated glomerular filtration rate and confers protection against the risk of chronic kidney disease stages G3–G5 and albuminuria, as shown in a study.
Jairia Dela Cruz, 16 May 2020
Excess weight, greater abdominal fat, inflammation and low physical performance can all contribute to insulin resistance in middle-age Singaporean women, and these variables explain why the condition is more common among women of Chinese than Malay and Indian ethnicities, a study has found.