Most Read Articles
Roshini Claire Anthony, 5 days ago

Patients with mild hypertension who are at low risk for cardiovascular disease (CVD) do not appear to derive mortality or CVD benefit from antihypertensive treatments, raising questions on the need for treatment in this population, according to a recent study from England.

Pearl Toh, 09 Nov 2018
A personalized computerized neurofeedback intervention for training attention and memory shows potential in cognitive training for healthy elderly men, who improved in cognitive performance after the training, although no significant improvements were seen in the overall study population.
3 days ago
Type 1 diabetes impairs cognitive functioning in children, and this effect is exacerbated by extreme glycaemic levels, according to a recent meta-analysis.
Pearl Toh, 08 Nov 2018
The pneumonia-causing bacteria, Streptococcus pneumoniae (pneumococcus), can be spread through nose picking and rubbing after exposure of the hands to the bacteria — in addition to the conventionally known route of inhalation of airborne droplets, a study reveals.

Para-aortic radiation ups risk of diabetes in testicular cancer survivors

15 Oct 2018
The latest Linear Accelerator (LINAC) technology is capable of zeroing in on a tumor and minimizing damage to surrounding cells.

Para-aortic irradiation appears to increase the risk of diabetes among testicular cancer (TC) survivors compared to surgery only, suggests a recent study.

There were 161 TC survivors diagnosed with diabetes during a median follow-up of 13.4 years. Risk of diabetes was not higher compared to general population rates (standardized incidence ratios [SIR], 0.9; 95 percent CI, 0.7–1.1).

Para-aortic radiotherapy correlated with a 1.66-fold (1.05–2.62) increased risk of diabetes compared to no radiotherapy after adjustment for age. For every 10-Gy increase in the prescribed radiation dose, the excess hazard increased by 0.31 (0.11–0.51; p=0.003), adjusted for age and body mass index. In irradiated patients, the excess hazard increased by 0.33 (–0.14 to 0.81; p=0.169) with every 10-Gy increase in radiation dose.

Apart from diabetes risk, an earlier study also found a dose-response relationship between radiotherapy and pancreatic cancer risk among TC survivors. Researchers noted that such excesses, although small, must be taken into account when radiotherapy with exposure to the pancreas is considered for newly diagnosed patients. [Br J Cancer 2016;115:901-908]

In the present study, the investigators analysed the risk of diabetes in 2,998 1-year TC survivors treated before 50 years of age with orchidectomy with/without radiotherapy between 1976 and 2007. They also compared the incidence of diabetes with general population rates. A case-cohort design was used to assess treatment-specific diabetes risk.

TC is considered the most curable solid tumour, with a 10-year survival rate of more than 95 percent, according to a study by Travis and colleagues. [J Natl Cancer Inst 2010;102:1114-1130]

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Most Read Articles
Roshini Claire Anthony, 5 days ago

Patients with mild hypertension who are at low risk for cardiovascular disease (CVD) do not appear to derive mortality or CVD benefit from antihypertensive treatments, raising questions on the need for treatment in this population, according to a recent study from England.

Pearl Toh, 09 Nov 2018
A personalized computerized neurofeedback intervention for training attention and memory shows potential in cognitive training for healthy elderly men, who improved in cognitive performance after the training, although no significant improvements were seen in the overall study population.
3 days ago
Type 1 diabetes impairs cognitive functioning in children, and this effect is exacerbated by extreme glycaemic levels, according to a recent meta-analysis.
Pearl Toh, 08 Nov 2018
The pneumonia-causing bacteria, Streptococcus pneumoniae (pneumococcus), can be spread through nose picking and rubbing after exposure of the hands to the bacteria — in addition to the conventionally known route of inhalation of airborne droplets, a study reveals.