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Overactive bladder puts damper on hypertension management in men

4 days ago

In the management of hypertension, men with overactive bladder (OAB) are less likely to achieve blood pressure (BP) control than their peers who do not have the urological condition, according to a study.

The cross-sectional study used data from the sixth follow-up exam (2015–2016) of the Multi-Ethnic Study of Atherosclerosis. A total of 1,446 men and 1,628 women who completed the International Consultation on Incontinence Questionnaire (ICIQ) were included in the analysis.

The mean age of the population was 73.7 years. OAB was detected in 31.6 percent of men and 38.9 percent of women. Multivariable sex-stratified regression models showed that in the group of participants not taking BP-lowering medications, OAB was not associated with systolic BP or diastolic BP in both men and women.

However, in the group of 894 men and 981 women on antihypertensive medication, OAB correlated with elevated systolic BP levels among men (4.04 mm Hg, 95 percent confidence interval [CI] 1.02–7.06) but not among women (−0.67 mm Hg, 95 percent CI, −3.79–2.46). This association was not seen for diastolic BP.

OAB lowered the odds of achieving BP control for men (odds ratio [OR], 0.69, 95 percent CI, 0.49–0.96) but not women (OR, 0.96, 95 percent CI, 0.71–1.30).

The present data suggest that OAB may impede hypertension management in men.

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Most Read Articles
Pearl Toh, 3 days ago
Not only does the CGRP* inhibitor galcanezumab show sustained efficacy in migraine patients, long-term treatment does not come with excess cardiovascular (CV) risk, according to studies presented at the AAN 2021 Annual Meeting.
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Migraine and headache are common ailments of people living in the modern era. Dr Jon Marshall of The Singapore Headache and Migraine Clinic shares his insights with Pearl Toh on how to manage migraine and headache using non-pharmaceutical strategies, with a focus on the manual medicine approach.
Tristan Manalac, 5 days ago
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