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Overactive bladder helps predict falls older adults

10 Jan 2021

An overactive bladder, with (wet) or without urgency incontinence (dry), can significantly predict falls in older adults with a low absolute fall risk, suggests a study.

The authors conducted this prospective cohort study in 630 community-dwelling, independent older adults aged 75 years who attended a health check-up in 2017 with a 1-year follow-up. Logistic regression models were used to assess the associations of overactive bladder dry and wet with a fall history, as well as future fall risk compared to no overactive bladder.

In total, 577 participants (median age, 79 years; 47 percent men) were included in the analysis. The prevalence of overactive bladder dry and wet at baseline was 15 percent and 14 percent, respectively.

In multivariable logistic regression analysis, both overactive bladder dry (adjusted odds ratio [aOR], 2.03, 95 percent confidence interval [CI], 1.23–3.37) and wet (aOR, 2.21, 95 percent CI, 1.29–3.78) correlated with an increased likelihood of prior falls.

Among participants without a fall history (n=363), the adjusted ORs of overactive bladder dry and wet for the occurrence of falls were 2.74 (95 percent CI, 1.19–6.29) and 1.35 (95 percent CI, 0.47–3.87), respectively, during the 1-year follow-up.

In the tree-based approach used for all participants, overactive bladder was a significant predictor of falls in adults without a fall history. The model had an accuracy of 83.6 percent and area under the receiver operating characteristic curve of 81.8 percent.

Editor's Recommendations
Most Read Articles
05 Feb 2021

Primary immunodeficiency disease (PIDD) and allergies are two groups of conditions related to the immune system. However, they are uniquely different in terms of symptoms and treatment.

Roshini Claire Anthony, 5 days ago

Switching from tenofovir disoproxil fumarate (TDF) to tenofovir alafenamide (TAF) did not result in worsening renal function or bone mineral density (BMD) in Asian patients with chronic hepatitis B virus (HBV) infection, according to a small real-world prospective study.

5 days ago
The standard combination therapy against paediatric migraine—consisting of a combination of parenteral medications—appears to yield moderate pain relief, which persists up to 1 week after administration, a new study has found.
Roshini Claire Anthony, 3 days ago

Critical or severe COVID-19 disease could raise the risk of negative perinatal outcomes in pregnant women, according to an observational study from the US.