Most Read Articles
Roshini Claire Anthony, 5 days ago

Patients with mild hypertension who are at low risk for cardiovascular disease (CVD) do not appear to derive mortality or CVD benefit from antihypertensive treatments, raising questions on the need for treatment in this population, according to a recent study from England.

Pearl Toh, 09 Nov 2018
A personalized computerized neurofeedback intervention for training attention and memory shows potential in cognitive training for healthy elderly men, who improved in cognitive performance after the training, although no significant improvements were seen in the overall study population.
3 days ago
Type 1 diabetes impairs cognitive functioning in children, and this effect is exacerbated by extreme glycaemic levels, according to a recent meta-analysis.
Pearl Toh, 08 Nov 2018
The pneumonia-causing bacteria, Streptococcus pneumoniae (pneumococcus), can be spread through nose picking and rubbing after exposure of the hands to the bacteria — in addition to the conventionally known route of inhalation of airborne droplets, a study reveals.

Outcomes for splanchnic vein thrombosis poor in patients with liver cirrhosis

05 Sep 2018

The risk of long-term and recurrent thrombotic events is elevated in cirrhotic patients with splanchnic vein thrombosis (SVT), a recent study has found.

A total of 604 consecutive SVT patients were enrolled in the study, of whom 149 (median age 59 years; 71.1 percent) were cirrhotic. Incidence rates of major bleeding, all-cause mortality and thrombotic events over a 2-year period were collected. Kaplan-Meier curves were constructed to evaluate overall survival rates, while Cox proportional hazards regression analyses were performed to identify potential predictors of the outcomes.

Nineteen cases of major bleeding were recorded during the follow-up period, resulting in an overall incidence rate of 9.8 per 100 patient-years. Major bleeding became progressively more common in patients with higher disease severity (Child-Pugh class A, B and C: 6.8, 15.4 and 33 cases per 100 patient-years, respectively).

In comparison, 25 thrombotic events were observed and yielded an incidence rate of 12.9 per 100 patient-years. Participants with more severe liver diseases were similarly more likely to suffer from recurrent vascular events.

The same was true for mortality, such as those with Child-Pugh class A diseases were less likely to die than those with class C liver disease. Overall, there were 42 deaths reported with an incidence rate of 17.5 per 100 patient-years.

Multivariable analysis revealed that ascites (hazard ratio [HR], 5.65; 95 percent CI, 1.92–16.64; p=0.002), a history of prior venous thromboembolism (HR, 14.73; 2.11–102.83; p=0.007) and a diagnosis of hepatocellular carcinoma (HR, 6.24; 2.45–15.85; p<0.001) were all associated with a significantly higher risk of mortality.

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Most Read Articles
Roshini Claire Anthony, 5 days ago

Patients with mild hypertension who are at low risk for cardiovascular disease (CVD) do not appear to derive mortality or CVD benefit from antihypertensive treatments, raising questions on the need for treatment in this population, according to a recent study from England.

Pearl Toh, 09 Nov 2018
A personalized computerized neurofeedback intervention for training attention and memory shows potential in cognitive training for healthy elderly men, who improved in cognitive performance after the training, although no significant improvements were seen in the overall study population.
3 days ago
Type 1 diabetes impairs cognitive functioning in children, and this effect is exacerbated by extreme glycaemic levels, according to a recent meta-analysis.
Pearl Toh, 08 Nov 2018
The pneumonia-causing bacteria, Streptococcus pneumoniae (pneumococcus), can be spread through nose picking and rubbing after exposure of the hands to the bacteria — in addition to the conventionally known route of inhalation of airborne droplets, a study reveals.