Most Read Articles
20 Jun 2020
The Lundbeck Neuroscience Symposium was held at Sofitel KL Damansara over 2 days, with extensivediscussions on the management of various mental illnesses. The second day of the symposiumaddressed the topic of schizophrenia management, focusing on treatment goals, the rationale forpartial dopamine D(2) receptor agonism and the use of long-acting injectable (LAI) antipsychotics topromote adherence.
Pearl Toh, 3 days ago
Having migraine during midlife appears to be associated with a higher risk of developing dementia in later life, according to a large population-based longitudinal Danish study presented at the AHS* 2020 Virtual Meeting, indicating that migraine may be a risk factor for dementia.
2 days ago
Patients with psoriatic arthritis (PsA) often suffer from liver abnormalities, which are associated with higher body mass index (BMI), daily consumption of alcohol, more severe disease, and some therapies, according to a recent study.
Christina Lau, Yesterday

Pembrolizumab in combination with chemotherapy significantly improves progression-free survival (PFS) vs chemotherapy alone in patients with previously untreated, locally recurrent inoperable or metastatic triple-negative breast cancer (TNBC), results of the KEYNOTE-355 study have shown.

Omphalomesenteric duct remnant rarely occurs but must be examined in infants

09 Nov 2019

The presence of omphalomesenteric duct (OMD) is quite rare in infants, but clinicians are advised to consider this remnant while examining patients with umbilical abnormalities, according to a recent study, noting that mismanagement may lead to severe morbidity and mortality.

“Meticulous inspection of the umbilicus at birth might reveal a persisting embryonic remnant, such as an OMD, manifested by a variety of cutaneous signs, such as an umbilical mass, granulation tissue or discharge,” the investigators said.

This study sought to evaluate the available data regarding the presence and management of OMD remnant with cutaneous involvement to propose a practical approach for diagnosis and treatment. The investigators performed a systematic review of the literature evaluating OMD anomalies presenting with cutaneous symptoms. Apart from this, they also presented an index case of an 11-month-old patient.

Fifty-nine publications, which included a total of 536 patients, met the inclusion criteria. Of the patients whose age was noted, 97 percent were infants (mean age, 11 months).

Diagnosis was established in 7.5 percent of patients only after treatment failure. Nonlethal complications were reported in 6.4 percent of patients. In addition, nearly one in 10 infants (10.3 percent) succumbed to death, partly due to either delayed diagnosis or mismanagement.

This study had certain limitations, which included limited quality of the collected data and potential bias, according to the investigators.

“Disorders of the umbilicus are commonly seen in infancy, including hernias, infections, anomalies, granulomas and malignancies,” they noted.

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Most Read Articles
20 Jun 2020
The Lundbeck Neuroscience Symposium was held at Sofitel KL Damansara over 2 days, with extensivediscussions on the management of various mental illnesses. The second day of the symposiumaddressed the topic of schizophrenia management, focusing on treatment goals, the rationale forpartial dopamine D(2) receptor agonism and the use of long-acting injectable (LAI) antipsychotics topromote adherence.
Pearl Toh, 3 days ago
Having migraine during midlife appears to be associated with a higher risk of developing dementia in later life, according to a large population-based longitudinal Danish study presented at the AHS* 2020 Virtual Meeting, indicating that migraine may be a risk factor for dementia.
2 days ago
Patients with psoriatic arthritis (PsA) often suffer from liver abnormalities, which are associated with higher body mass index (BMI), daily consumption of alcohol, more severe disease, and some therapies, according to a recent study.
Christina Lau, Yesterday

Pembrolizumab in combination with chemotherapy significantly improves progression-free survival (PFS) vs chemotherapy alone in patients with previously untreated, locally recurrent inoperable or metastatic triple-negative breast cancer (TNBC), results of the KEYNOTE-355 study have shown.