Most Read Articles
18 May 2020
Immobilization or disuse of the forearm leads to impairment in the ability of a protein-rich meal to promote positive muscle amino acid balance, which is aggravated by dietary lipid oversupply, suggests a study. Disuse also lowers postprandial forearm amino acid uptake, but this is not exacerbated under high-fat conditions.
18 May 2020
Glucagon-like peptide-1 receptor agonists (GLP-1RA) are more effective than basal insulin in the management of total (TC) and low-density lipoprotein cholesterol (LDL-C), reveals a recent study.
17 May 2020
Increased coffee consumption among regular drinkers is associated with higher estimated glomerular filtration rate and confers protection against the risk of chronic kidney disease stages G3–G5 and albuminuria, as shown in a study.
Jairia Dela Cruz, 16 May 2020
Excess weight, greater abdominal fat, inflammation and low physical performance can all contribute to insulin resistance in middle-age Singaporean women, and these variables explain why the condition is more common among women of Chinese than Malay and Indian ethnicities, a study has found.

Omphalomesenteric duct remnant rarely occurs but must be examined in infants

09 Nov 2019

The presence of omphalomesenteric duct (OMD) is quite rare in infants, but clinicians are advised to consider this remnant while examining patients with umbilical abnormalities, according to a recent study, noting that mismanagement may lead to severe morbidity and mortality.

“Meticulous inspection of the umbilicus at birth might reveal a persisting embryonic remnant, such as an OMD, manifested by a variety of cutaneous signs, such as an umbilical mass, granulation tissue or discharge,” the investigators said.

This study sought to evaluate the available data regarding the presence and management of OMD remnant with cutaneous involvement to propose a practical approach for diagnosis and treatment. The investigators performed a systematic review of the literature evaluating OMD anomalies presenting with cutaneous symptoms. Apart from this, they also presented an index case of an 11-month-old patient.

Fifty-nine publications, which included a total of 536 patients, met the inclusion criteria. Of the patients whose age was noted, 97 percent were infants (mean age, 11 months).

Diagnosis was established in 7.5 percent of patients only after treatment failure. Nonlethal complications were reported in 6.4 percent of patients. In addition, nearly one in 10 infants (10.3 percent) succumbed to death, partly due to either delayed diagnosis or mismanagement.

This study had certain limitations, which included limited quality of the collected data and potential bias, according to the investigators.

“Disorders of the umbilicus are commonly seen in infancy, including hernias, infections, anomalies, granulomas and malignancies,” they noted.

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Most Read Articles
18 May 2020
Immobilization or disuse of the forearm leads to impairment in the ability of a protein-rich meal to promote positive muscle amino acid balance, which is aggravated by dietary lipid oversupply, suggests a study. Disuse also lowers postprandial forearm amino acid uptake, but this is not exacerbated under high-fat conditions.
18 May 2020
Glucagon-like peptide-1 receptor agonists (GLP-1RA) are more effective than basal insulin in the management of total (TC) and low-density lipoprotein cholesterol (LDL-C), reveals a recent study.
17 May 2020
Increased coffee consumption among regular drinkers is associated with higher estimated glomerular filtration rate and confers protection against the risk of chronic kidney disease stages G3–G5 and albuminuria, as shown in a study.
Jairia Dela Cruz, 16 May 2020
Excess weight, greater abdominal fat, inflammation and low physical performance can all contribute to insulin resistance in middle-age Singaporean women, and these variables explain why the condition is more common among women of Chinese than Malay and Indian ethnicities, a study has found.