Most Read Articles
Pearl Toh, 10 Oct 2019
Adding a LAMA* to the double combination therapy of ICS** plus LABA*** in a single inhaler improves lung function and reduces exacerbations in patients whose asthma is inadequately controlled with the combination treatment, according to the TRIMARAN and TRIGGER# studies presented at ERS 2019.
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Tristan Manalac, 3 days ago
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Omega-3 fatty acids ineffective against bronchopulmonary dysplasia in preemies

07 Jul 2019

Use of omega-3 long-chain polyunsaturated fatty acids (N-3 LCPUFAs) proves to be unsuccessful at preventing bronchopulmonary dysplasia (BPD) in preterm infants, according to the results of a meta-analysis.

Researchers searched multiple online databases for randomized controlled trials (RCTs) evaluating the effect of intervention with N-3 LCPUFAs (initiated within 1 month of birth) on the incidence of BPD or oxygen dependency for 28 days after birth or 36 weeks’ postmenstrual age in preterm infants (<37 weeks of gestation).

The meta-analysis included 14 trials, which involved 3,531 preterm infants in total. Pooled data revealed that N-3 LCPUFAs conferred no beneficial effect on the incidence of BPD in preterm infants (risk ratio, 0.99; 95 percent CI, 0.84–1.18; p=0.93).

Results were similar in subgroup analyses stratified by gestational age, birth weight, dosage of docosahexaenoic acid and duration of intervention.

The current findings provide no supporting evidence for current recommendations to administer N-3 LCPUFAs routinely, according to the researchers, who acknowledged that the main limitation of the meta-analysis is that the populations, protocols and pharmaceutical ingredients of N-3 LCPUFAs vary among the included trials.

More studies with larger sample sizes and long-term follow-up data are needed to establish whether the efficacy of N-3 LCPUFAs on BPD is affected by populations, protocols and the specific pharmaceutical ingredients of N-3 LCPUFAs, they added.

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Most Read Articles
Pearl Toh, 10 Oct 2019
Adding a LAMA* to the double combination therapy of ICS** plus LABA*** in a single inhaler improves lung function and reduces exacerbations in patients whose asthma is inadequately controlled with the combination treatment, according to the TRIMARAN and TRIGGER# studies presented at ERS 2019.
4 days ago
Eating alone may help in weight management as findings of a recent study suggest that eating with friends lead to higher food intake.
Tristan Manalac, 3 days ago
A digital-first approach, iConnect, allows patients to have greater access to services and guidance and enables healthcare providers to deliver much better postdischarge care, according to Lim Cher Wee, chief operating officer of the Ministry of Health, Office for Healthcare Transformation of Singapore, in his presentation at the recently concluded AsiaPac19 Conference & Exhibition of the Healthcare Information and Management Systems Society (HIMSS 2019).
Jairia Dela Cruz, 3 days ago
Toileting behaviours such as convenience and delayed voiding, straining to void, and position preference are strongly associated with overactive bladder (OAB) symptoms in women, according to a study.