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Older age, arrhythmia predict impaired processing speed in stroke survivors

11 Feb 2019

Impaired processing speed (IPS) in stroke survivors may persist long after the index event, a study reports. Some of the baseline factors that predict IPS include older age, arrhythmia, previous stroke and coronary artery disease.

Researchers assessed IPS using the Symbol Digit Modalities Test (SDMT) 4 years after stroke in a cohort of 133 survivors (mean age 67.0 years). Baseline factors potentially associated with IPS were determined at time of stroke and/or within 2 weeks of the acute event.

Long-term IPS was highly prevalent, with 62 percent of survivors having a mean SDMT score <40 at 4 years after stroke.

Multivariable regression models revealed the following baseline variables as significant predictors of long-term IPS: arrhythmia (odds ratio [OR], 4.40; 95 percent CI, 1.5–12.4; p=0.01), coronary artery disease (OR, 3.35; 1.6–9.6; p=0.01), older age (OR, 3.03; 0.9–9.3; p=0.05), previous stroke (OR, 2.74; 1.0–7.4; p=0.05), cholesterol (OR, 2.72; 1.3–5.4; p=0.01) and hypertension (OR, 1.82; 0.9–3.6; p=0.05).

Findings of the present study may aid in identification of stroke patients who are at higher risk of IPS, researchers said. Early identification is especially important to target rehabilitation interventions and improve overall outcomes.

IPS affects up to 70 percent of stroke survivors and exerts a huge influence on poststroke cognitive dysfunction, leading to a poor quality of life and increased dependence on others, they added.

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Most Read Articles
09 Jul 2019
Patients who had undergone aortic valve replacement (AVR) have shorter life expectancy than the general population, a study has found. Apart from being substantial, this loss in life expectancy increases with younger age.
3 days ago
The consumption of red and processed meats does not seem to affect the likelihood of symptom relapse among Crohn’s disease (CD) patients in relapse, reports a recent study.
Roshini Claire Anthony, 6 days ago

Women who receive a single dose of amoxicillin and clavulanic acid within 6 hours of operative vaginal delivery could significantly reduce their postpartum infection risk, according to the UK-based ANODE* trial.

3 days ago
Treatment with metformin may improve whole-body and peripheral insulin resistance (IR) in youth who are overweight/obese with type 1 diabetes (T1D), according to a study.