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01 Dec 2019
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The presence of pulmonary arterial hypertension (PAH) in individuals with systemic sclerosis is associated with an increased mortality risk, a study from Singapore showed.

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23 Dec 2019
At a Menarini-sponsored symposium held during the Asian Pacific Society Congress, renowned cardiologist Prof John Camm provided the latest evidence for chronic stable angina with or without concomitant diseases, with a special focus on the antianginal agent ranolazine and combination therapies. The event was chaired and moderated by Dr Dante Morales from the University of the Philippines College of Medicine.

Occasional napping may promote cardiovascular health

03 Oct 2019

Napping one to two times per week appears to be protective against the risk of developing cardiovascular disease (CVD) events, according to a recent study. No such association is observed for any napping duration.

The study included 3,462 individuals with no previous history of CVD. Of these, 2,014 individuals (58 percent) reported that they did not nap during the previous week, 667 (19 percent) took 1–2 naps, 411 (12 percent) took 3–5 naps and 370 (11 percent) took 6–7 naps.

Compared with non-nappers, frequent nappers (3–7 times weekly) were older, more likely to be men, to have a lower educational status, to frequently smoke, and had a higher body mass index and longer nocturnal sleep duration. Additionally, those who napped frequently experienced excessive daytime sleepiness and presented with more severe obstructive sleep apnoea.

A total of 155 fatal and nonfatal CVD events occurred over a mean follow-up of 5.3 years. Unadjusted Cox proportional hazard analysis revealed that the risk of incident CVD was significantly lower in individuals who napped 1–2 times weekly (hazard ratio [HR], 0.39, 95 percent CI, 0.21–0.72) and elevated in those taking 6-7 naps weekly (HR, 1.67, 1.10–2.55) compared with non-nappers.

In multivariate models, the protective association between occasional napping and CVD incidence risk remained significant (HR, 0.52, 0.28–0.95), whereas the risk increase associated with frequent napping disappeared (HR, 0.89, 0.58–1.38).

Neither obstructive sleep apnoea nor excessive daytime sleepiness modified the protective benefit of occasional napping. Furthermore, nap duration showed no association with CVD events.

The discrepant findings regarding the association between napping and CVD events may be explained by nap frequency, according to researchers.

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Most Read Articles
01 Dec 2019
Macrolide antibiotics are derived from the Streptomycesspecies. These contain either 14-membered (erythromycin [ERM],clarithromycin [CAM], roxithromycin [RXM]), 15-membered(azithromycin [AZM]) or 16-membered (spiramycin, josamycin,midecamycin) macrocyclic lactone rings. They inhibit proteinsynthesis by reversibly binding to the 23S ribosomal RNA (rRNA)in the 50s subunit of the bacterial ribosome. Traditionally,macrolides are used as first-line agents in respiratory, skin,soft tissue, and urogenital infections, and they are also activeagainst gram-positive cocci and atypical pathogens.
Roshini Claire Anthony, 6 days ago

The presence of pulmonary arterial hypertension (PAH) in individuals with systemic sclerosis is associated with an increased mortality risk, a study from Singapore showed.

01 Dec 2019
Pneumonia is a common infection– affecting around 3,200 people inSingapore in 2016 – making it the thirdmost common cause of hospitalisation inthe country. Its common complications,especially with delayed or inappropriatetreatment, include bacteraemia andseptic shock, lung abscesses, pleuraleffusions, empyema, pleurisy, respiratoryfailure and renal failure.
23 Dec 2019
At a Menarini-sponsored symposium held during the Asian Pacific Society Congress, renowned cardiologist Prof John Camm provided the latest evidence for chronic stable angina with or without concomitant diseases, with a special focus on the antianginal agent ranolazine and combination therapies. The event was chaired and moderated by Dr Dante Morales from the University of the Philippines College of Medicine.