Most Read Articles
Roshini Claire Anthony, Yesterday

Patients undergoing chemotherapy for breast or haematological cancers could potentially reduce their risk of chemotherapy-related cardiotoxicity with the use of angiotensin-converting enzyme (ACE) inhibitors, angiotensin II receptor antagonists (ARBs), or beta-blockers as primary prevention, according to a systematic review and meta-analysis presented at the recent EuroEcho 2019 conference.

29 Nov 2019
Metformin Extended Release 500 mg,750 mg, and 1000 mg
6 days ago
Men who undergo flexible cystoscopy, particularly with a longer dwell time, may benefit from intraurethral lidocaine as it provides significant pain reduction, suggest the results of a meta-analysis. Evidence is lacking for other tested interventions.
Tristan Manalac, 2 days ago
Users of electronic nicotine delivery systems are likely to have received a diagnosis of clinical depression in the past, according to a recent study.

Obesity protects against diabetic retinopathy in type 2 diabetes

12 Jun 2019

In patients with type 2 diabetes, obesity may be protective against vision-threatening diabetic retinopathy (DR), a recent Korea study has shown.

Researchers enrolled 887 participants with type 2 diabetes into a nationwide survey. Seven-field fundus photographs were used to evaluate for the presence and severity of DR, while body fat was measured using dual-energy X-ray absorptiometry.

Only 185 participants (median age, 63 years; 42.2 percent male) were diagnosed with DR, while the rest were not (n=702; median age, 65 years; 50.3 percent male). Body mass index (BMI; p=0.001) and waist circumference (p=0.024) were significantly greater in those without DR. This trend was reflected for total body fat, but significance was not achieved (p=0.102).

Multivariate logistic regression analysis showed that BMI (adjusted odds ratio [OR], 0.80, 95 percent CI, 0.70–0.92; p=0.001) and waist circumference (adjusted OR, 0.86, 0.79–0.92; p<0.001) were significantly correlated with a lower likelihood of vision-threatening DR.

Obesity remained significantly predictive against DR risk when the Asian BMI cutoff values were used (adjusted OR, 0.65, 0.43–0.99; p-trend=0.029), as well as when participants were divided into tertiles of waist circumference (highest vs lowest: adjusted OR, 0.54, 0.32–0.91; p-trend=0.009).

Stratification of all analyses according to sex showed that total body fat remained significantly associated with DR risk only in females (adjusted OR, 0.93, 0.88–0.98; p=0.009). No such effect was observed in males or with the other obesity indices used.

Editor's Recommendations
Most Read Articles
Roshini Claire Anthony, Yesterday

Patients undergoing chemotherapy for breast or haematological cancers could potentially reduce their risk of chemotherapy-related cardiotoxicity with the use of angiotensin-converting enzyme (ACE) inhibitors, angiotensin II receptor antagonists (ARBs), or beta-blockers as primary prevention, according to a systematic review and meta-analysis presented at the recent EuroEcho 2019 conference.

29 Nov 2019
Metformin Extended Release 500 mg,750 mg, and 1000 mg
6 days ago
Men who undergo flexible cystoscopy, particularly with a longer dwell time, may benefit from intraurethral lidocaine as it provides significant pain reduction, suggest the results of a meta-analysis. Evidence is lacking for other tested interventions.
Tristan Manalac, 2 days ago
Users of electronic nicotine delivery systems are likely to have received a diagnosis of clinical depression in the past, according to a recent study.