Most Read Articles
Roshini Claire Anthony, 08 Apr 2019

About one-third of individuals who achieved remission of type 2 diabetes (T2D) after losing weight with an intensive weight management programme sustained their remission at 2 years, according to long-term results of the DiRECT* trial.

6 days ago
Progressive lipolysis may be reduced via the improved antilipolytic effect in adipose tissue, which leads to a reduction in future weight loss caused by sodium-glucose cotransporter 2 inhibitors (SGLT2is) in patients with type 2 diabetes (T2D), suggests a recent study.
06 Aug 2019
Maternal prepregnancy obesity is associated with earlier age at voice break, pubic hair development, axillary hair and acne in sons, as well as with earlier age at menarche, breast development, pubic hair development, axillary hair and acne in daughters, a study has found. These associations appear to be mediated by higher childhood body mass index in sons and partly so in daughters.
15 Feb 2018
Long-term treatment with dual-release hydrocortisone (DR-HC) appears to produce favourable effects on insulin secretion and sensitivity in patients with prediabetes, according to a study. The treatment also confers benefits for metabolic and anthropometric parameters.

Obesity may constrain physical function, activities among older adults

16 May 2019

Due to the increasing global prevalence of obesity, older adults may live more years of their remaining life with limited physical function and activities in daily living (ADLs), according to a study, adding that older adults, their families and healthcare systems should be aware of this problem.

Life expectancy (LE) at age 60 years was comparable for individuals with normal weight, preobesity and obesity, but those with obesity vs normal weight had 6.3 (95 percent CI, 3.4–9.2) more years with limitation in physical function and 4.9 (3.4–6.5) less years without limitation in physical function. Individuals with preobesity vs normal weight also had 3.7 (1.9–5.3) more years with limitation in physical function.

There was a similar pattern for years of life with and without limitation in ADLs across the categories of body mass index (BMI). Stratified analyses revealed similar association of BMI with years of life with and without limitation in physical function and in ADLs across gender, ethnicity and educational status.

This study used longitudinal data on 3,452 older (≥60 years) Singaporeans to examine the relationship between BMI and years of remaining life overall with and without limitation in physical function and in ADLs. Difficulty in any task involving upper or lower extremities was deemed as limitation in physical function, and health-related difficulty in any basic or instrumental ADL as limitation in ADLs. Multistate life tables, including BMI as a time-varying covariate, was used.

“While older adults with preobesity and class I obesity have similar or lower mortality risk vs those with normal weight, a heavier BMI may not translate into more healthy life years,” the authors said.

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Most Read Articles
Roshini Claire Anthony, 08 Apr 2019

About one-third of individuals who achieved remission of type 2 diabetes (T2D) after losing weight with an intensive weight management programme sustained their remission at 2 years, according to long-term results of the DiRECT* trial.

6 days ago
Progressive lipolysis may be reduced via the improved antilipolytic effect in adipose tissue, which leads to a reduction in future weight loss caused by sodium-glucose cotransporter 2 inhibitors (SGLT2is) in patients with type 2 diabetes (T2D), suggests a recent study.
06 Aug 2019
Maternal prepregnancy obesity is associated with earlier age at voice break, pubic hair development, axillary hair and acne in sons, as well as with earlier age at menarche, breast development, pubic hair development, axillary hair and acne in daughters, a study has found. These associations appear to be mediated by higher childhood body mass index in sons and partly so in daughters.
15 Feb 2018
Long-term treatment with dual-release hydrocortisone (DR-HC) appears to produce favourable effects on insulin secretion and sensitivity in patients with prediabetes, according to a study. The treatment also confers benefits for metabolic and anthropometric parameters.