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Nutritional intervention not effective for preventing weight gain following kidney transplant

25 Aug 2018
Hospital Authority is set to introduce a pair exchange scheme for kidney transplants by the second half of 2018.

Intensive nutrition intervention programmes are not better than standard nutrition care in preventing weight gain in kidney transplant recipients 1 year after the operation, a recent study has found.

The single-blind randomized controlled trial included 36 adult kidney transplant recipients who were randomly assigned to receive the intensive intervention (n=18; mean age 49.2±14.6 years; 67 percent male) or standard nutrition care (n=18; mean age 48.3±13.9 years; 72 percent male). Weight at 6 months after the transplant was the primary outcome.

Mean body weight for the whole cohort increased from 78.0±13.7 kg at baseline to 79.6±13.0 kg at 6 months and 81.6±12.6 kg at 12 months, reflecting a significant 4.6-percent increase.

Analysis of covariance showed that mean weight at 6 months was statistically similar between both groups (intervention: 77±12.4 kg; control: 82.2±13.4 kg; adjusted mean difference, 0.4 kg; 95 percent CI, –2.2 to 3.0 kg; p=0.7).

In terms of secondary outcomes, no significant group-by-time interaction was observed for body mass index (p=0.354), waist circumference (p=0.484), hip circumference (p=0.608), total body fat (p=0.697), total body protein (p=0.861), total body potassium (p=0.175), resting energy expenditure (p=0.260) and other measures of anthropometry and body composition.

Both intervention groups likewise yielded similar outcomes in terms of grip strength (p=0.986), gait speed (p=0.304), sit-to-stand-to-sit test scores (p=0.167) and weekly physical activity (p=0.602), indicating comparable efficacies in terms of physical function.

In comparison, control participants showed significantly better general-health quality of life between 6 and 12 months (p=0.003), while total energy intake significantly decreased from baseline to 6 months in the intervention group (p=0.02).

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Most Read Articles
5 days ago
A recent study reports a mean growth rate of proximal aorta of about 0.1 mm/year in hypertensive patients with known aortic dilatation. In addition, those with increased rather than normal aortic z score have slower dilatation over time.
Tristan Manalac, 4 days ago
The coronavirus disease 2019 (COVID-19) appears to be more dangerous among cancer patients, who tend suffer more severe complications and faster disease progression, according to a new study.
Roshini Claire Anthony, 3 days ago

Among patients with nonvalvular atrial fibrillation (AF), treatment with apixaban was associated with a lower rate of ischaemic stroke, systemic embolism, and major bleeding compared with rivaroxaban, according to a large study assessing patients in routine care.

Yesterday
Exposure to sunlight appears to increase the risk of vulvovaginal candidiasis (VVC) development, reveals a recent study in an African population.