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Nutritional intervention not effective for preventing weight gain following kidney transplant

25 Aug 2018
Hospital Authority is set to introduce a pair exchange scheme for kidney transplants by the second half of 2018.

Intensive nutrition intervention programmes are not better than standard nutrition care in preventing weight gain in kidney transplant recipients 1 year after the operation, a recent study has found.

The single-blind randomized controlled trial included 36 adult kidney transplant recipients who were randomly assigned to receive the intensive intervention (n=18; mean age 49.2±14.6 years; 67 percent male) or standard nutrition care (n=18; mean age 48.3±13.9 years; 72 percent male). Weight at 6 months after the transplant was the primary outcome.

Mean body weight for the whole cohort increased from 78.0±13.7 kg at baseline to 79.6±13.0 kg at 6 months and 81.6±12.6 kg at 12 months, reflecting a significant 4.6-percent increase.

Analysis of covariance showed that mean weight at 6 months was statistically similar between both groups (intervention: 77±12.4 kg; control: 82.2±13.4 kg; adjusted mean difference, 0.4 kg; 95 percent CI, –2.2 to 3.0 kg; p=0.7).

In terms of secondary outcomes, no significant group-by-time interaction was observed for body mass index (p=0.354), waist circumference (p=0.484), hip circumference (p=0.608), total body fat (p=0.697), total body protein (p=0.861), total body potassium (p=0.175), resting energy expenditure (p=0.260) and other measures of anthropometry and body composition.

Both intervention groups likewise yielded similar outcomes in terms of grip strength (p=0.986), gait speed (p=0.304), sit-to-stand-to-sit test scores (p=0.167) and weekly physical activity (p=0.602), indicating comparable efficacies in terms of physical function.

In comparison, control participants showed significantly better general-health quality of life between 6 and 12 months (p=0.003), while total energy intake significantly decreased from baseline to 6 months in the intervention group (p=0.02).

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Most Read Articles
Roshini Claire Anthony, 2 days ago

A subgroup of patients with HBeAg-negative chronic hepatitis B virus (HBV) infection who ceased their long-term nucleotide analogue treatment maintained virological suppression, pointing to a group of patients who may be suitable for treatment cessation, according to a recent study.

Rachel Soon, 4 days ago

Gels utilizing Stichopus horrens (golden sea cucumber/gamat) extract show a similar efficacy to standard-of-care hydrogels for promoting wound healing, according to a prospective study.

3 days ago
Higher cancer symptom burden in elderly adults is associated with functional impairment, reports a recent study.
Jairia Dela Cruz, 6 days ago
Use of mirabegron in the treatment of men with overactive bladder (OAB) appears to effectively alleviate urgency and storage symptoms, but not reduce the frequency of micturition episodes, according to data from the MIRACLE study.