Most Read Articles
05 Nov 2019
Low total cholesterol levels appear to carry increased major adverse cardiovascular events (MACE) hazard in older men without ischaemic heart disease (IHD) and not receiving statin therapy but not to those on statins, according to data from the CHAMP (Concord Health and Ageing in Men Project) cohort.
Yesterday
Better sleep appears to weaken pain and fatigue in older, community-dwelling adults with hip or knee osteoarthritis (OA), reports a recent study.
5 days ago
Maribavir 400 mg twice daily appears to have comparable efficacy to valganciclovir at clearing cytomegalovirus viraemia in transplant recipients, a study has found.
4 days ago
Individuals with and without gout appear to have a similar risk of developing colorectal cancer, suggesting that gout does not contribute to a risk increase, a study has found.

Nulliparous women with low cervical dilation more likely to need more anaesthetic interventions

01 Nov 2019

A single injection of spinal anaesthesia appears to be enough for multiparous women undergoing spontaneous labour with more advanced cervical dilation, a recent study has found.

Researchers retrospectively reviewed electronic medical records of 428 women (median age, 30 years) who received spinal analgesic blocks for labour. The primary outcome was the need for an additional anaesthetic intervention after the first administration of analgesia. Spinal, epidural and general anaesthesia, as well as intravenous sedation, were counted.

Sixty instances of required additional anaesthetic intervention were reported, resulting in an overall rate of 14.0 percent. The median time to additional administration was 115 minutes. These patients showed significantly longer time to delivery than their counterparts who did not require any additional anaesthetics (222 vs 48 minutes; p<0.001).

Multivariable logistic regression analysis found that higher age (odds ratio [OR] per 5 years, 1.41, 95 percent CI, 1.04–1.90; p=0.025), nulliparity (OR, 3.33, 1.72–6.43; p<0.001) and having low cervical dilation (OR per 1 cm, 0.87, 0.76–1.00; p=0.045) were all significant predictors for needing additional anaesthetic interventions.

Complications were rare (n=9; 2.1 percent) and were limited to postdural puncture headaches. Of those who developed the side effect, more than half (n=5; 55.6 percent) received successful epidural blood patches. There were no reports of neurologic or bleeding complications, and none of the participating women required treatment for pruritus.

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Doctor - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
05 Nov 2019
Low total cholesterol levels appear to carry increased major adverse cardiovascular events (MACE) hazard in older men without ischaemic heart disease (IHD) and not receiving statin therapy but not to those on statins, according to data from the CHAMP (Concord Health and Ageing in Men Project) cohort.
Yesterday
Better sleep appears to weaken pain and fatigue in older, community-dwelling adults with hip or knee osteoarthritis (OA), reports a recent study.
5 days ago
Maribavir 400 mg twice daily appears to have comparable efficacy to valganciclovir at clearing cytomegalovirus viraemia in transplant recipients, a study has found.
4 days ago
Individuals with and without gout appear to have a similar risk of developing colorectal cancer, suggesting that gout does not contribute to a risk increase, a study has found.