Most Read Articles
Roshini Claire Anthony, 11 Sep 2019

Beta-blockers could reduce mortality risk in patients with heart failure with reduced ejection fraction (HFrEF) and moderate or moderately-severe renal dysfunction without causing harm, according to the BB-META-HF* trial presented at ESC 2019.

Elvira Manzano, 3 days ago

The US Preventive Services Task Force (USPSTF), in an update of its 2013 recommendations, called on clinicians to offer risk-reducing medications to women who are at increased risk for breast cancer but at low risk for adverse effects.

Pearl Toh, 4 days ago
The use of SGLT-2* inhibitors was not associated with a higher risk of severe or nonsevere urinary tract infections (UTIs) in patients with type 2 diabetes (T2D) compared with DPP**-4 inhibitors or GLP-1*** receptor agonists, a population-based cohort study shows.
14 Sep 2019
In type 2 diabetes patients taking sulfonylureas, hypoglycaemia duration is longer at night and is inversely correlated with the level of glycated haemoglobin (HbA1c), a new study reports.

Novel tool developed to assess, monitor cough

12 Jun 2019

Researchers have recently developed and validated the effectiveness of Cough Assessment Test (COAT), a simple questionnaire used to evaluate and monitor cough.

This study sought to create a short patient-completed questionnaire, which was developed through reliability test and validated in comparison with the Korean version of Leicester Cough Questionnaire (K-LCQ) and cough numeric rating scale (NRS, 0–10; 11-point scale) for chronic cough patients.

A selection process identified five items about cough frequency, daily activity, sleep disturbance, fatigue and cough hypersensitivity (0–4 scaling of the items, 0–20 score range) to develop COAT, which was then tried in a reliability test cohort (n=78).

Internal consistency was excellent (Cronbach’s a, 0.84), and test retest repeatability was very good (intraclass correlation coefficient, 0.88). The final COAT was compared with K-LCQ and cough NRS in a validation cohort (n=323).

Rasch analysis revealed that COAT fitted well to a unidimensional model. Pearson correlations were –0.71 for COAT vs K-LCQ before treatment and –0.81 after treatment, 0.69 for COAT vs cough NRS before treatment and –0.82 after treatment, –0.66 for delta-COAT vs delta-cough NRS, and 0.72 for delta-COAT vs delta-K-LCQ.

“A cough‐specific quality‐of‐life questionnaire is recommended to assess the impact of cough,” the investigators said. “[H]owever, a simple instrument to quantify cough is required for everyday clinical practice.”

A previous systematic review and meta-analysis found that several instruments for assessing cough severity, frequency and impact on quality of life demonstrate good internal consistency but variable correlation with other cough measurement tools. This means that while some instruments are precise, their accuracy is less clear. [AHRQ Comparative Effectiveness Reviews 2013;Report No:13-EHC032-EF]

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Most Read Articles
Roshini Claire Anthony, 11 Sep 2019

Beta-blockers could reduce mortality risk in patients with heart failure with reduced ejection fraction (HFrEF) and moderate or moderately-severe renal dysfunction without causing harm, according to the BB-META-HF* trial presented at ESC 2019.

Elvira Manzano, 3 days ago

The US Preventive Services Task Force (USPSTF), in an update of its 2013 recommendations, called on clinicians to offer risk-reducing medications to women who are at increased risk for breast cancer but at low risk for adverse effects.

Pearl Toh, 4 days ago
The use of SGLT-2* inhibitors was not associated with a higher risk of severe or nonsevere urinary tract infections (UTIs) in patients with type 2 diabetes (T2D) compared with DPP**-4 inhibitors or GLP-1*** receptor agonists, a population-based cohort study shows.
14 Sep 2019
In type 2 diabetes patients taking sulfonylureas, hypoglycaemia duration is longer at night and is inversely correlated with the level of glycated haemoglobin (HbA1c), a new study reports.