Most Read Articles
Roshini Claire Anthony, 11 Sep 2019

Beta-blockers could reduce mortality risk in patients with heart failure with reduced ejection fraction (HFrEF) and moderate or moderately-severe renal dysfunction without causing harm, according to the BB-META-HF* trial presented at ESC 2019.

Prof. Vincent Wong, Prof. Ray Kim, Dr. Tan Poh Seng, 10 Sep 2019
Chronic hepatitis B (CHB) remains a major public health concern because of its worldwide distribution and potential adverse sequelae, including cirrhosis and hepatocellular carcinoma (HCC). At a recent symposium held during the GIHep Singapore 2019, Professor Vincent Wong from the Chinese University of Hong Kong and Professor Ray Kim from the Stanford University School of Medicine, Stanford, California, US, discussed antiviral treatments for CHB, with a focus on the novel agent tenofovir alafenamide (Vemlidy®). Dr Tan Poh Seng from the National University Hospital, Singapore, chaired the symposium.
11 Sep 2019
Blood pressure (BP) in children is influenced by early-life exposure to several chemicals, built environment and meteorological factors, suggests a study.
Pearl Toh, Yesterday
The use of SGLT-2* inhibitors was not associated with a higher risk of severe or nonsevere urinary tract infections (UTIs) in patients with type 2 diabetes (T2D) compared with DPP**-4 inhibitors or GLP-1*** receptor agonists, a population-based cohort study shows.

No link between H. pylori infection and carotid intima-media thickness

09 Oct 2018

There appears to be no meaningful link between Helicobacter pylori infection and carotid intima-media thickness (CIMT) in the general population, according to a recent China study.

Researchers enrolled 13,770 individuals who had undergone both the H. pylori test and CIMT measurements. A minority of the study population tested positive for the infection (39.3 percent; n=5,418; mean age 52.0±12.1 years; 62.5 percent male) while most (n=9,741) did not have increased CIMT.

In those who were positive for the infection, 28.6 percent (n=1,549) showed increased CIMT. This was not significantly different than in those who were negative for the infection (n=8,352; mean age 52.8±12.8 years; 58.5 percent male), of whom 29.7 percent (n=2,480) had increased CIMT (p=0.164).

Conversely, there was no significant difference in the rate of H. pylori infection among those with and without increased CIMT (38.4 percent vs 39.7 percent; p=0.164).

This was further confirmed in binary logistic regression analysis, which showed no significant relationship between CIMT and H. pylori infection status even after adjustments for covariates such as waistline, total cholesterol, blood pressure, fasting plasma glucose and body mass index, among other (odds ratio [OR], 1.118; 95 percent CI, 0.958–1.306; p=0.157).

While the present findings suggest that H. pylori infections are unrelated to CIMT, future, larger studies involving other strains are needed to determine the involvement of the bacteria in atherosclerosis, said researchers.

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Most Read Articles
Roshini Claire Anthony, 11 Sep 2019

Beta-blockers could reduce mortality risk in patients with heart failure with reduced ejection fraction (HFrEF) and moderate or moderately-severe renal dysfunction without causing harm, according to the BB-META-HF* trial presented at ESC 2019.

Prof. Vincent Wong, Prof. Ray Kim, Dr. Tan Poh Seng, 10 Sep 2019
Chronic hepatitis B (CHB) remains a major public health concern because of its worldwide distribution and potential adverse sequelae, including cirrhosis and hepatocellular carcinoma (HCC). At a recent symposium held during the GIHep Singapore 2019, Professor Vincent Wong from the Chinese University of Hong Kong and Professor Ray Kim from the Stanford University School of Medicine, Stanford, California, US, discussed antiviral treatments for CHB, with a focus on the novel agent tenofovir alafenamide (Vemlidy®). Dr Tan Poh Seng from the National University Hospital, Singapore, chaired the symposium.
11 Sep 2019
Blood pressure (BP) in children is influenced by early-life exposure to several chemicals, built environment and meteorological factors, suggests a study.
Pearl Toh, Yesterday
The use of SGLT-2* inhibitors was not associated with a higher risk of severe or nonsevere urinary tract infections (UTIs) in patients with type 2 diabetes (T2D) compared with DPP**-4 inhibitors or GLP-1*** receptor agonists, a population-based cohort study shows.