Most Read Articles
Roshini Claire Anthony, 5 days ago

Individuals with moderate-to-severe plaque psoriasis may reap better long-term improvements in the severity of their condition when treated with guselkumab over secukinumab, according to findings of the phase III ECLIPSE* trial presented at the recent Inflammatory Skin Disease Summit (ISDS 2018) held in Vienna, Austria.

Jairia Dela Cruz, 11 Jan 2019
Use of standard-dose aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs) appears to confer protection against the risk of endometrial cancer in overweight and obese women, according to a meta-analysis.
4 days ago
Discontinuing the use of tyrosine kinase inhibitors (TKIs) in the treatment of patients with chronic myeloid leukaemia appears to be feasible in real-life clinical practice in the context of close molecular monitoring, a study reports.
5 days ago
There appears to be no clear link between pornography use, even at problematic levels, and erectile dysfunction, a recent US study has shown.

Nitrate intake linked to lower risk of early age-related macular degeneration

02 Nov 2018

Total nitrate intake, especially from vegetable sources, is associated with the incidence of early age-related macular degeneration (AMD), reports a new Australia study.

Using a semi-quantitative food frequency questionnaire, researchers evaluated the dietary intake of 2,856 adults. Follow-up after 15 years was conducted on 2,037 participants (mean age 63.8±8.3 years; 43.3 percent male). AMD incidence, the main study outcome, was assessed from retinal photographs.

At baseline, 12.4 percent of the participants were current smokers and more than half (59.4 percent) consumed at least one serving of fish per week. The incidence rates of early and late AMD were 15.3 percent and 4.1 percent, respectively.

Dividing participants into quartiles according to energy-adjusted daily nitrate intake, researchers showed that those in the third quartile (119.5–162.3 mg/day; adjusted odds ratio [OR], 0.61; 95 percent CI, 0.41–0.90; p<0.05) were significantly less likely to develop early AMD than those in the first quartile. No significant differences were observed for the second and fourth quartiles (p=0.19 for trend).

Stratified analysis according to nitrate source showed that the protective effect of being in the third quartile remained significant for vegetable nitrates (adjusted OR, 0.65; 0.44–0.96; p<0.05) but not for nonvegetable nitrates (adjusted OR, 0.79; 0.54–1.17).

On the other hand, nitrate consumption was consistently unrelated to the risk of late AMD, regardless of source of daily intake volume.  

Though future studies are still required to confirm and strengthen the present conclusions, the findings of the current study indicate that adopting diets rich in nitrate sources such as beetroot and green leafy vegetables may potentially be a simple strategy to minimize early AMD risk, said researchers.

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Doctor - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
Roshini Claire Anthony, 5 days ago

Individuals with moderate-to-severe plaque psoriasis may reap better long-term improvements in the severity of their condition when treated with guselkumab over secukinumab, according to findings of the phase III ECLIPSE* trial presented at the recent Inflammatory Skin Disease Summit (ISDS 2018) held in Vienna, Austria.

Jairia Dela Cruz, 11 Jan 2019
Use of standard-dose aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs) appears to confer protection against the risk of endometrial cancer in overweight and obese women, according to a meta-analysis.
4 days ago
Discontinuing the use of tyrosine kinase inhibitors (TKIs) in the treatment of patients with chronic myeloid leukaemia appears to be feasible in real-life clinical practice in the context of close molecular monitoring, a study reports.
5 days ago
There appears to be no clear link between pornography use, even at problematic levels, and erectile dysfunction, a recent US study has shown.