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3 days ago
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Jairia Dela Cruz, 3 days ago
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Roshini Claire Anthony, Yesterday

Upadacitinib may be a suitable treatment for patients with active psoriatic arthritis (PsA) who have insufficient response to non-biologic disease-modifying anti-rheumatic drugs (non-bDMARDs), according to results of the phase III SELECT-PsA-1* trial presented at EULAR 2020.

Nine-valent human papillomavirus vaccine shows favourable safety profile

26 Dec 2019

Safety data of the 9-valent human papillomavirus vaccine (9vHPV) from the Vaccine Adverse Event Reporting System (VAERS) during the first 3 years of its licensure in the United States have shown neither new or unexpected safety signals, nor unusual reporting patterns for clinically important adverse events (AEs), as reported in a study. Furthermore, the safety profile of the vaccine is similar to that of its quadrivalent predecessor.

VAERS documented 7,244 AEs following receipt of 9vHPV. Of the AEs, 31.2 percent occurred among females and 21.6 percent among males; sex was not reported in 42.7 percent.

Majority (97.4 percent) of the AEs were nonserious, the most common being dizziness, syncope, headache and injection site reactions. These AEs occurred with similar frequency in men and women. There were two verified cases of deaths post-9vHPV treatment, although autopsy reports or death certificates suggested no evidence of a causal relationship with vaccination.

Roughly 28 million 9vHPV doses were administered during the study period, giving crude AE reporting rates of 259 reports per million doses distributed for all reports and 7 per million doses distributed for serious reports.

Empirical Bayesian data mining findings showed a significant association between 9vHPV and syncope and several types of vaccine administration errors (eg, administered at wrong age).

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Most Read Articles
3 days ago
Routinely used for treating cardiovascular diseases, statins have been shown to benefit other conditions, and new evidence suggests that using the drug at high intensity reduces the risk of hip or knee replacement, an effect that may be specific to rheumatoid arthritis.
Jairia Dela Cruz, 3 days ago
Following vegan and vegetarian diets, which offer plenty of what is good for health, has been reported to have a downside: an increased risk of depression and anxiety, especially for younger adults.
Pearl Toh, 29 Jun 2020
Having migraine during midlife appears to be associated with a higher risk of developing dementia in later life, according to a large population-based longitudinal Danish study presented at the AHS* 2020 Virtual Meeting, indicating that migraine may be a risk factor for dementia.
Roshini Claire Anthony, Yesterday

Upadacitinib may be a suitable treatment for patients with active psoriatic arthritis (PsA) who have insufficient response to non-biologic disease-modifying anti-rheumatic drugs (non-bDMARDs), according to results of the phase III SELECT-PsA-1* trial presented at EULAR 2020.