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New Mediterranean, DASH-based diet improves glycaemic control

28 Aug 2020

An investigational diet plan based on the Mediterranean and DASH* diets may help improve glycaemic control in adults with type 2 diabetes (T2D), a recent study has found.

The researchers conducted a 12-week open-label randomized clinical trial including 53 adults with T2D. Group A (n=16) received the investigational diet, and groups B (n=20) and C (n=17) took a food exchange system (FES)-based diet given as a ready meal or not, respectively. The primary endpoint was the change in glycated haemoglobin (HbA1c) over 12 weeks of intervention.

Patients in group A saw a mean HbA1c change of –0.84±0.73 percent from baseline to week 6. In the full analysis set, this represented a significantly greater decrease than in groups B (p=0.021) and C (p=0.003). The mean change values over the same time span in the respective groups were –0.39±0.39 percent and –0.23±0.42 percent.

By week 12, group A participants logged a mean HbA1c change of –0.97±0.97 percent relative to baseline. In groups B and C, the average change values were –0.51±0.65 percent and –0.36±0.75 percent, respectively. Per-protocol analysis revealed that those in group A saw a significantly greater decrease in HbA1c (p=0.028 and p=0.02, respectively).

The researchers found that the investigational diet was similarly superior to the FES comparators in terms of the other indicators: 6-week fasting plasma glucose, 6-week C-reactive protein, and lipid profile, among others.

 *Dietary Approaches to Stop Hypertension

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Most Read Articles
30 Aug 2020
Diabetes bears an increased hazard of developing kidney cancer among postmenopausal women, but this association is only limited to those without obesity, a study has shown.
11 Jul 2020
Individuals who eat large amounts of vegetables and fruits, wheat, nuts, and dairy products are better protected against insulin resistance, diabetes mellitus, and excessive abdominal fat as compared with those who consume lots of fast foods, alcoholic beverages, and desserts—a dietary pattern described to promote metabolic abnormalities and disorders, as reported in a study.
22 Aug 2020
A weakened correlation between fructosamine and glycated haemoglobin (HbA1c) levels may be indicative of obesity in type 2 diabetes patients, reports a new study.
29 Aug 2020
Sodium-glucose co-transporters (SGLT) 2 and 1/2 inhibitors help improve glycaemic control in patients with type 1 diabetes (T1D), reports a new meta-analysis.