Most Read Articles
06 Apr 2018

Female patients with coronary artery disease (CAD) have greater regression of coronary atherosclerosis than male patients despite a lower plaque burden at baseline, data from the GLAGOV trial have shown.

26 Apr 2018
Transcatheter aortic valve replacement (TAVR) in severe symptomatic aortic stenosis (AS) patients is superior to conventional surgical aortic valve replacement (SAVR) in terms of reducing life-threatening bleeding, new-onset atrial fibrillation and acute kidney injury, a recent meta-analysis has found.
Jairia Dela Cruz, 03 May 2018
Acute coronary syndrome (ACS) patients with diabetes mellitus, as well as high-risk nondiabetic patients, appear to obtain significant cardioprotection from the addition of ezetimibe to simvastatin, and this benefit is achieved without compromising safety, according to an exploratory analysis of data from IMPROVE-IT (Improved Reduction of Outcomes: Vytorin Efficacy International Trial).
04 May 2018
Sudden cardiac arrest (SCA) occurs in the absence of warning symptoms in most patients, with sports being a trigger of SCA in some cases, a study suggests. Furthermore, standard cardiovascular risk factors are highly prevalent in SCA in the young, and all of these factors are preventable.

Neutrophil-to-lymphocyte ratio predicts myocardial injury after noncardiac surgery

12 May 2018
The more painful the surgery, the more likely addiction is, according to a report by the research firm QuintilesIMS Institute for Healthcare Informatics

The neutrophil-to-lymphocyte ratio (NLR) appears to be a simple and easy method for predicting the development of myocardial injury after noncardiac surgery (MINS), a recent study has shown.

Peak high-sensitivity cardiac troponin T (hs-cTnT; 126.6 vs 7.5; p<0.000), mean neutrophil count (6,498±819 vs 5,978±998 mm-3; p=0.007) and median C-reactive protein (CRP) levels (3.0 vs 2.5; p=0.02) were significantly higher in those with vs without MINS, as was mean NLR (3.79±0.7 vs 2.69±0.6; p<0.0001).

In contrast, lymphocyte count was significantly lower in patients with MINS (1,857±331 vs 2,038±391 mm-3; p=0.016).

Moreover, multivariate logistic regression analysis showed that the variables independently and significantly associated with MINS were age (odds ratio [OR], 1.081; 95 percent CI, 1.004–1.165; p=0.039), CRP concentration (OR, 1.552; 1.009–2.386; p=0.045), lymphocyte count (OR, 1.002; 1.001–1.004; p=0.040) and NLR (OR, 11.690; 4.619–29.585; p<0.000).

At a cutoff value of 3.3, receiver operating characteristic analysis showed that NLR could predict MINS with an 80-percent sensitivity and 84-percent specificity (area under the curve, 0.85; 0.78–0.93).

The findings of the present study support the use of preoperative NLR as an easy, inexpensive and noninvasive marker for the detection of patients at high risk of cardiac complications after noncardiac surgery.

Using blood samples collected from 255 patients who underwent noncardiac surgery after a 12-hour fast, researchers measured CRP, glucose and triglyceride levels, along with blood cell counts. Electrocardiography and hs-cTnT measurements were performed immediately after surgery and at 1 and 3 days after surgery.

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Most Read Articles
06 Apr 2018

Female patients with coronary artery disease (CAD) have greater regression of coronary atherosclerosis than male patients despite a lower plaque burden at baseline, data from the GLAGOV trial have shown.

26 Apr 2018
Transcatheter aortic valve replacement (TAVR) in severe symptomatic aortic stenosis (AS) patients is superior to conventional surgical aortic valve replacement (SAVR) in terms of reducing life-threatening bleeding, new-onset atrial fibrillation and acute kidney injury, a recent meta-analysis has found.
Jairia Dela Cruz, 03 May 2018
Acute coronary syndrome (ACS) patients with diabetes mellitus, as well as high-risk nondiabetic patients, appear to obtain significant cardioprotection from the addition of ezetimibe to simvastatin, and this benefit is achieved without compromising safety, according to an exploratory analysis of data from IMPROVE-IT (Improved Reduction of Outcomes: Vytorin Efficacy International Trial).
04 May 2018
Sudden cardiac arrest (SCA) occurs in the absence of warning symptoms in most patients, with sports being a trigger of SCA in some cases, a study suggests. Furthermore, standard cardiovascular risk factors are highly prevalent in SCA in the young, and all of these factors are preventable.