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Jairia Dela Cruz, 3 days ago
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Neurogenic bladder amplifies complication risk after implantable penile prosthesis placement

4 days ago

Men with neurogenic bladder (NGB) are at higher risk of complications after placement of implantable penile prostheses (IPPs), a recent study has shown.

Researchers retrieved the records of 37 men with NGB (median age, 48 years) who underwent IPP placement. Study endpoints included surgical outcomes, complications, and the use of medications such as anticholinergic or beta-3 agonists. A parallel group of 267 men without NGB (median age, 62 years), but who received IPPs for erectile dysfunction, was also included.

In both groups, most of the participants underwent IPP placement for the first time under study enrollment. The most common causes for NGB in the study cohort were spinal cord injuries (46.0 percent), spine surgery (23.3 percent), and multiple sclerosis (10.8 percent).

Complications occurred significantly more frequently in NGB participants than in controls (24.3 percent vs 7.5 percent; p=0.001). Specific complications, such as mechanical problems, erosion, and infection, remained more prevalent in the NGB group.

Multivariate logistic regression analysis confirmed that NGB was a strong and significant risk factor for the development of IPP complications (odds ratio [OR], 3.47, 95 percent confidence interval [CI], 1.13–10.71; p=0.03).

Chronic obstructive pulmonary disease also emerged as a significant risk factor (OR, 3.88, 95 percent CI, 1.39–10.79; p=0.009), while those who underwent IPP placement for the first time were at a reduced risk of complications (OR, 0.25, 95 percent CI, 0.09–0.71; p=0.01).

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Most Read Articles
Jairia Dela Cruz, 3 days ago
In patients with heart failure with reduced ejection fraction (HFrEF) receiving angiotensin-converting-enzyme (ACE) inhibitors, high dosing confers benefits for the risk of death or hospitalization that are similar to that obtained with lower dosing, according to a systematic review and meta-analysis.
06 Sep 2020
Type 2 diabetes mellitus patients taking proton pump inhibitors (PPIs) are at a higher risk of sustaining hip fractures, a recent study has found.
5 days ago
Osteoarthritis (OA) is the most common condition affecting the joints. Dr Lee Eu Jin, an Orthopaedic Surgeon from Liberty Orthopaedic Clinic at Mount Elizabeth Medical Centre, Singapore, shares his insights with Pearl Toh on how to manage OA in the primary care setting.


4 days ago
XOFLUZA – Baloxavir marboxil 20 mg and 40 mg FC tab