Most Read Articles
01 Dec 2019
Macrolide antibiotics are derived from the Streptomycesspecies. These contain either 14-membered (erythromycin [ERM],clarithromycin [CAM], roxithromycin [RXM]), 15-membered(azithromycin [AZM]) or 16-membered (spiramycin, josamycin,midecamycin) macrocyclic lactone rings. They inhibit proteinsynthesis by reversibly binding to the 23S ribosomal RNA (rRNA)in the 50s subunit of the bacterial ribosome. Traditionally,macrolides are used as first-line agents in respiratory, skin,soft tissue, and urogenital infections, and they are also activeagainst gram-positive cocci and atypical pathogens.
Roshini Claire Anthony, 6 days ago

The presence of pulmonary arterial hypertension (PAH) in individuals with systemic sclerosis is associated with an increased mortality risk, a study from Singapore showed.

01 Dec 2019
Pneumonia is a common infection– affecting around 3,200 people inSingapore in 2016 – making it the thirdmost common cause of hospitalisation inthe country. Its common complications,especially with delayed or inappropriatetreatment, include bacteraemia andseptic shock, lung abscesses, pleuraleffusions, empyema, pleurisy, respiratoryfailure and renal failure.
23 Dec 2019
At a Menarini-sponsored symposium held during the Asian Pacific Society Congress, renowned cardiologist Prof John Camm provided the latest evidence for chronic stable angina with or without concomitant diseases, with a special focus on the antianginal agent ranolazine and combination therapies. The event was chaired and moderated by Dr Dante Morales from the University of the Philippines College of Medicine.

Neurogastroenterology tests factor in avoidant/restrictive food intake disorder

23 Nov 2019

Patients undergoing neurogastroenterology examinations commonly present with symptoms of avoidant/restrictive food intake disorder (ARFID) driven mostly by fear of gastrointestinal symptoms, as shown in a recent study.

Researchers retrospectively examined the medical records of 410 consecutive individuals referred (aged 18–90 years; 73.0 percent female) to a tertiary care centre for neurogastroenterology examination.

Twenty-six individuals (6.3 percent) met the full criteria for ARFID, while 71 (17.3 percent) had clinically significant avoidant or restrictive eating behaviours but insufficient information for a definitive ARFID diagnosis.

Most of the patients with ARFID symptoms (90/97; 92.8 percent) endorsed fear of gastrointestinal symptoms as motivation for their avoidant or restrictive eating.

Binary logistic regressions showed that likelihood of having ARFID symptoms was significantly high in patients with eating- or weight-related complaints (odds ratio [OR], 5.09, 95 percent confidence interval [CI], 2.54–10.21); those presenting with dyspepsia, nausea or vomiting (OR, 3.59, 95 percent CI, 2.04–6.32); those with abdominal pain (OR, 4.72, 95 percent CI, 1.87–11.81); and those with more than one diagnosis of a gastrointestinal disorder (OR, 1.63, 95 percent CI, 1.26–2.10).

“ARFID is a feeding and eating disorder that is characterized by avoidant or restrictive eating not primarily motivated by body shape or weight concerns,” according to the researchers. The present data highlight the importance of evaluating patients undergoing neurogastroenterology or motility examinations for symptoms of ARFID.

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Most Read Articles
01 Dec 2019
Macrolide antibiotics are derived from the Streptomycesspecies. These contain either 14-membered (erythromycin [ERM],clarithromycin [CAM], roxithromycin [RXM]), 15-membered(azithromycin [AZM]) or 16-membered (spiramycin, josamycin,midecamycin) macrocyclic lactone rings. They inhibit proteinsynthesis by reversibly binding to the 23S ribosomal RNA (rRNA)in the 50s subunit of the bacterial ribosome. Traditionally,macrolides are used as first-line agents in respiratory, skin,soft tissue, and urogenital infections, and they are also activeagainst gram-positive cocci and atypical pathogens.
Roshini Claire Anthony, 6 days ago

The presence of pulmonary arterial hypertension (PAH) in individuals with systemic sclerosis is associated with an increased mortality risk, a study from Singapore showed.

01 Dec 2019
Pneumonia is a common infection– affecting around 3,200 people inSingapore in 2016 – making it the thirdmost common cause of hospitalisation inthe country. Its common complications,especially with delayed or inappropriatetreatment, include bacteraemia andseptic shock, lung abscesses, pleuraleffusions, empyema, pleurisy, respiratoryfailure and renal failure.
23 Dec 2019
At a Menarini-sponsored symposium held during the Asian Pacific Society Congress, renowned cardiologist Prof John Camm provided the latest evidence for chronic stable angina with or without concomitant diseases, with a special focus on the antianginal agent ranolazine and combination therapies. The event was chaired and moderated by Dr Dante Morales from the University of the Philippines College of Medicine.