Most Read Articles
Rachel Soon, 05 Dec 2018

At the recent Malaysian Community Pharmacy Business Forum (MyCPBF), a discussion forum was held on the subject of “Transcending Primary Healthcare Services: The Future of Specialized Pharmacy Services and Pharmacy Specialization”.

17 Feb 2019
In patients with type 2 diabetes (T2D), sodium-glucose cotransporter 2 (SGLT2) inhibitor monotherapy, particularly canagliflozin, exerts greater effects on weight compared with metformin and dipeptidyl peptidase 4 (DPP-4) inhibitors or gliptins, according to the results of a meta-analysis.
Roshini Claire Anthony, 20 Mar 2018

Individuals with type 2 diabetes (T2D) who initiate therapy with sodium glucose cotransporter-2 (SGLT-2) inhibitors have lower risks of all-cause death and cardiovascular (CV) outcomes, specifically myocardial infarction (MI) and stroke, compared with those who initiate other glucose-lowering therapies, according to results from the CVD-REAL* 2 study.

Pearl Toh, 09 Mar 2019
The need for postoperative morphine consumption was not reduced even with the concurrent use of low-dose S-ketamine in patients who were undergoing major open gynaecological surgeries using remifentanil–propofol target-controlled infusion (TCI), a local study finds.

Nanotechnology structured water shows potential for ED treatment

Audrey Abella
11 May 2018

Nanotechnology structured water was similarly effective as tadalafil in improving erectile function, suggesting that it could be a potential treatment option for erectile dysfunction (ED), according to a study presented at EAU held in Copenhagen, Denmark.

“Nanotechnology structured water … is a new type of water that is prepared using different types of energy fields and modulators to produce this nanotechnology structured water that has new and different characteristics from ordinary water,” said the researchers.

A total of 262 men with ED were randomized to receive a daily dose of nanotechnology structured water 20 mL/kg body weight (group A, n=87), tadalafil 5 mg (group B, n=90), or ordinary bottled water 20 mL/kg (group C, n=85) and completed a 3-month evaluation. [EAU 2018, abstract 591]

The degree of ED and treatment success were determined by using the International Index of Erectile Function-Erectile Function (IIEF-EF) domain (questions 1–5, and question 15), Sexual Encounter Profile questions 1 and 2 (SEP1 and SEP2), and Global Assessment questions 1 and 2 (GAQ1 and GAQ2) related to erectile function.

At 3 months, group A participants exhibited significant improvements from baseline in IIEF-EF (from 14.39 to 22.64; p<0.001), SEP1 (from 62 percent to 83 percent; p<0.001), SEP2 (from 35 percent to 77 percent; p<0.001), GAQ1 (85 percent; p<0.001) and GAQ2 (79 percent; p<0.001).

Group B showed similar improvements at 3 months in terms of IIEF-EF (from 13.89 to 27.38; p<0.001), SEP1 (from 60 percent to 89 percent; p<0.001), SEP2 (from 37 percent to 85 percent; p<0.001), GAQ1 (91 percent; p<0.001), and GAQ2 (84 percent; p<0.001).

These findings reflect similar efficacy between nanotechnology structured water and tadalafil, noted the researchers. “Nanotechnology structured water … is a novel way to treat ED patients without the need for expensive medications with no side effects … [and] offers a reasonable and safe way to treat ED,” they said.

The results also support previous evidence reflecting the role of nanotechnology-based vehicles in translational therapy development for diseases such as ED, as it has a unique design for drug delivery and is believed to enhance growth factor effects by providing a platform that offers improved release, penetration, and bioavailability, as well as a localized and sustained method of delivery. [J Sex Med 2017;14:36-43; J Urol 1994;151:54-61; J Sex Med 2004;1:284-1291]

 

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Most Read Articles
Rachel Soon, 05 Dec 2018

At the recent Malaysian Community Pharmacy Business Forum (MyCPBF), a discussion forum was held on the subject of “Transcending Primary Healthcare Services: The Future of Specialized Pharmacy Services and Pharmacy Specialization”.

17 Feb 2019
In patients with type 2 diabetes (T2D), sodium-glucose cotransporter 2 (SGLT2) inhibitor monotherapy, particularly canagliflozin, exerts greater effects on weight compared with metformin and dipeptidyl peptidase 4 (DPP-4) inhibitors or gliptins, according to the results of a meta-analysis.
Roshini Claire Anthony, 20 Mar 2018

Individuals with type 2 diabetes (T2D) who initiate therapy with sodium glucose cotransporter-2 (SGLT-2) inhibitors have lower risks of all-cause death and cardiovascular (CV) outcomes, specifically myocardial infarction (MI) and stroke, compared with those who initiate other glucose-lowering therapies, according to results from the CVD-REAL* 2 study.

Pearl Toh, 09 Mar 2019
The need for postoperative morphine consumption was not reduced even with the concurrent use of low-dose S-ketamine in patients who were undergoing major open gynaecological surgeries using remifentanil–propofol target-controlled infusion (TCI), a local study finds.