Most Read Articles
Roshini Claire Anthony, 4 days ago

The combined use of piperacillin and tazobactam does not appear to be a suitable alternative to meropenem for patients with bloodstream infections caused by ceftriaxone-resistant Escherichia coli (E. coli) or Klebsiella pneumoniae (K. pneumoniae), according to results of the MERINO* trial.

Tristan Manalac, 19 May 2018
Taking oral antibiotics appears to increase the risk of nephrolithiasis, according to a recent study. Moreover, the risk seems to be compounded for individuals with recent antibiotic exposure and those who were exposed at a younger age.
2 days ago
Patients with inflammatory bowel disease are at increased risk of developing acute myocardial infarction (AMI) or heart failure, although the prevalence of traditional risk factors for such cardiovascular disorders appears to be low, as reported in a recent study.
3 days ago
Early renin-angiotensin-aldosterone system (RAAS) blockade with renin-angiotensin system inhibitors (RASI) leads to better short- and long-term renal outcomes in systemic lupus erythematosus (SLE) patients with antiphospholipid-associated nephropathy (aPLN), according to a study, adding that this renal protective effect is independent of RASI’s antihypertensive and antiproteinuric effects.

Myopic choroidal neovascularization eyes exhibit larger increases in axial length

18 Jul 2017
Recently, researchers made a breakthrough discovery by developing a revolutionary eye-drop as a new treatment for age-related blindness.

In a Japanese population, highly myopic eyes show greater increases in axial length than nonmyopic eyes, a new retrospective longitudinal study shows. In particular, eyes with myopic choroidal neovascularization (CNV) show the greatest increases.

Over a median follow-up of 28.7±16.8 months, non-highly myopic eyes (n=85) showed significant increase in axial length from baseline to final examination (23.58±1.0 vs 23.60±1.0; p=0.008). The same trend was observed in highly myopic eyes.

Particularly, baseline and final examination axial length of eyes without complications (n=165; 29.01±1.6 vs 29.11±1.6; p<0.0001), eyes with myopic traction maculopathy (MTM; n=32; 29.16±1.7 vs 29.24±1.7; p<0.0001) and CNV eyes (n=34; 29.47±1.3 vs 29.66±1.3; p<0.0001) were significantly different from each other.

The change in axial length per year (mm/year) was significantly greater in highly myopic eyes without complications (0.041±0.05) than in non-highly myopic eyes (0.007±.02; p<0.0001). Change per year in MTM eyes (0.040±0.05) was not significantly different from no complication eyes (p=0.91).

On the other hand, CNV eyes (0.081±0.04) had significantly greater changes in axial length per year compared with MTM eyes (p=0.0059) and highly myopic eyes without complications (p<0.0001).

Females (p=0.04) and those with CNV (p<0.0001) had significantly greater chances of greater changes in axial length per year, according to multiple regression analysis.

A total of 316 eyes of 316 patients (mean age 63.8±9.0 years) with best-corrected visual acuity of 0.6 decimal fraction were included in the study. Eyes with severe cataracts, poor fixation and histories of surgery were excluded.

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Doctor - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
Roshini Claire Anthony, 4 days ago

The combined use of piperacillin and tazobactam does not appear to be a suitable alternative to meropenem for patients with bloodstream infections caused by ceftriaxone-resistant Escherichia coli (E. coli) or Klebsiella pneumoniae (K. pneumoniae), according to results of the MERINO* trial.

Tristan Manalac, 19 May 2018
Taking oral antibiotics appears to increase the risk of nephrolithiasis, according to a recent study. Moreover, the risk seems to be compounded for individuals with recent antibiotic exposure and those who were exposed at a younger age.
2 days ago
Patients with inflammatory bowel disease are at increased risk of developing acute myocardial infarction (AMI) or heart failure, although the prevalence of traditional risk factors for such cardiovascular disorders appears to be low, as reported in a recent study.
3 days ago
Early renin-angiotensin-aldosterone system (RAAS) blockade with renin-angiotensin system inhibitors (RASI) leads to better short- and long-term renal outcomes in systemic lupus erythematosus (SLE) patients with antiphospholipid-associated nephropathy (aPLN), according to a study, adding that this renal protective effect is independent of RASI’s antihypertensive and antiproteinuric effects.