Myopic choroidal neovascularization eyes exhibit larger increases in axial length
In a Japanese population, highly myopic eyes show greater increases in axial length than nonmyopic eyes, a new retrospective longitudinal study shows. In particular, eyes with myopic choroidal neovascularization (CNV) show the greatest increases.
Over a median follow-up of 28.7±16.8 months, non-highly myopic eyes (n=85) showed significant increase in axial length from baseline to final examination (23.58±1.0 vs 23.60±1.0; p=0.008). The same trend was observed in highly myopic eyes.
Particularly, baseline and final examination axial length of eyes without complications (n=165; 29.01±1.6 vs 29.11±1.6; p<0.0001), eyes with myopic traction maculopathy (MTM; n=32; 29.16±1.7 vs 29.24±1.7; p<0.0001) and CNV eyes (n=34; 29.47±1.3 vs 29.66±1.3; p<0.0001) were significantly different from each other.
The change in axial length per year (mm/year) was significantly greater in highly myopic eyes without complications (0.041±0.05) than in non-highly myopic eyes (0.007±.02; p<0.0001). Change per year in MTM eyes (0.040±0.05) was not significantly different from no complication eyes (p=0.91).
On the other hand, CNV eyes (0.081±0.04) had significantly greater changes in axial length per year compared with MTM eyes (p=0.0059) and highly myopic eyes without complications (p<0.0001).
Females (p=0.04) and those with CNV (p<0.0001) had significantly greater chances of greater changes in axial length per year, according to multiple regression analysis.
A total of 316 eyes of 316 patients (mean age 63.8±9.0 years) with best-corrected visual acuity of 0.6 decimal fraction were included in the study. Eyes with severe cataracts, poor fixation and histories of surgery were excluded.