Most Read Articles
Pearl Toh, 19 Jan 2018
Blood pressure (BP) control can be best achieved with a multilevel, multicomponent approach involving team-based care with physician- and non-physician-led interventions, as well as patient-level strategies, according to findings of a meta-analysis.
Pearl Toh, 09 Oct 2018
Not only are probiotics healthy for the gut, they may also be good for the waistline. A recent study shows that supplementation with the probiotic Bifidobacterium animalis subsp. lactis CECT 8145 (Ba8145) improves anthropometric adiposity measures such as waist circumference, body mass index (BMI), and visceral fat area in abdominally obese individuals, particularly in women.

Myocardial infarction after ECPR common among OHCA patients

11 Jun 2020

Myocardial infarction (MI) occurs frequently among patients with refractory out-of-hospital cardiac arrest (OHCA) receiving extracorporeal cardiopulmonary resuscitation (ECPR), a recent study has found.

Accessing a retrospective registry, researchers enrolled 252 patients (mean age, 59 years) who were given ECPR. The mean duration of venoarterial-extracorporeal membrane oxygenation (ECMO) was 131 hours, with a mean ECMO flow rate of 3.61 per minute after 24 hours.

Overall, 29 percent of the participants survived to hospital discharge and 75 percent underwent coronary angiography. MI type 1 was detected in 63 percent of the OCHA participants, a slightly greater prevalence rate than in their in-hospital cardiac arrest (IHCA) comparators (55 percent). The difference was not statistically significant.

MI type 2, defined as nonoccluded by severely stenosed coronary arteries, was diagnosed in less than 5 percent of the total sample. Similarly, no prevalence difference was reported between OHCA and IHCA.

Patients who developed MI type 1 had a survival outlook comparable to the overall cohort. In comparison, those with MI type 2 had a nominally worse survival rate (17 percent), but not significantly so (p=0.513). The researchers noted that this may partly be due to the smaller number of patients with MI type 2.

“Two-thirds of patients with refractory OHCA receiving ECPR had MI type 1 or 2 warranting immediate revascularization to salvage viable myocardium,” they said. “Considering that ECPR long-term survivors have a favourable neurological outcome, minimizing myocardial scarring and preventing subsequent heart failure appear of paramount importance.”

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Most Read Articles
Pearl Toh, 19 Jan 2018
Blood pressure (BP) control can be best achieved with a multilevel, multicomponent approach involving team-based care with physician- and non-physician-led interventions, as well as patient-level strategies, according to findings of a meta-analysis.
Pearl Toh, 09 Oct 2018
Not only are probiotics healthy for the gut, they may also be good for the waistline. A recent study shows that supplementation with the probiotic Bifidobacterium animalis subsp. lactis CECT 8145 (Ba8145) improves anthropometric adiposity measures such as waist circumference, body mass index (BMI), and visceral fat area in abdominally obese individuals, particularly in women.