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Product Highlight - Erleada

26 Jun 2020
For your patients with high risk# nmCRPC
Prescribing Erleada may help them delay metastasis and/or live longer1

Erleada is a potent androgen receptor (AR) inhibitor indicated for the treatment of patients with high risk non-metastasis castration-resistant prostate cancer (nmCRPC)

In the SPARTAN Study1:
  • Erleada +ADT improved median Metastasis Free Survival after (MFS) for more than 2 years (24.3 months) compared with placebo + ADT (40.5 months vs 16.2 months; HR=0.28; 95% CI: 0.23, 0.35; P<0.0001)1
  • Erleada + ADT when compared to ADT alone showed: 25% risk reduction in death and 51% risk reduction of PFS21
  • Erleada + ADT demonstrated statistically significant improvement in time to symptomatic progression, time to metastasis, PFS, time to PSA progression and PSA decline.1
  • Erleada provides convenience with once daily oral dosing.2
  • Erleada +ADT was well tolerated and maintained HRQoL of nmCRPC patients.1

#PSA doubling period ≤10 months; PFS: Progression Free Survival; ADT: Androgen deprivation therapy; PSA: Prostate specific antigen; HRQoL: Health-related Quality of Life


References:
1. Smith MR, et al. N Engl J Med. 2018;378(15):1408–18.
2. ERLEADA (apalutamide) approved prescribing information MalaysiaE uSmPC v Jan 2019


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Most Read Articles
Stephen Padilla, 2 days ago
The novel coronavirus disease (COVID-19) pandemic appears to have a significant impact on oncological care, according to a study, which stresses the need for psycho-oncological support for cancer patients.
01 Aug 2020
Supplementation with probiotics may have positive effects in patients with type 2 diabetes mellitus (T2DM), reports a recent meta-analysis.
01 Aug 2020
Ensituximab, a chimeric monoclonal antibody targeting a variant of MUC5AC, shows modest clinical activity with good safety profile in patients with refractory colorectal cancer, according to data from a phase II study.
Roshini Claire Anthony, 30 Jul 2020

Frailty may indicate an increased risk of death from COVID-19, results of the COPE* study showed.