Most Read Articles
Roshini Claire Anthony, 11 Feb 2020

The consumption of processed meat or unprocessed red meat may be associated with a slightly elevated risk of incident cardiovascular disease (CVD)* and all-cause mortality, according to a US study.

Jairia Dela Cruz, 25 Nov 2019
Use of the PCSK9* inhibitor alirocumab in acute coronary syndrome (ACS) patients on a background of high-intensity statin treatment delivers reductions in total hospitalizations and death with corresponding gains in days alive and out of hospital (DAOH), according to the results of prespecified and posthoc analyses of the ODYSSEY OUTCOMES** trial presented at the American Heart Association (AHA) 2019 Scientific Sessions.
Roshini Claire Anthony, 06 Feb 2020

The presence of metabolic syndrome* appears to increase the risk of recurrent venous thromboembolism (VTE)** among patients with deep vein thrombosis (DVT), a recent study showed.

Jairia Dela Cruz, 13 Feb 2020
For regular drinkers with atrial fibrillation (AF), cutting down alcohol consumption confers beneficial effects on both the AF burden and risk of recurrence, according to a recent study.

Multiple arterial graft for multivessel disease tied to lower mortality at 7 years

12 Sep 2019
AGGF1 allows non-surgical therapeutic angiogenesis through autophagy for coronary artery disease

Multiple (MAG) and single arterial coronary bypass grafts (SAG) for multivessel disease result in similar rates of mortality, as well as the composite outcome of mortality, stroke and acute myocardial infarction (MI), according to a study. However, these outcomes are lower for MAG after 7 years.

In addition, patients of higher volume MAG surgeons had lower MAG mortality.

A total of 63,402 multivessel disease patients undergoing coronary artery bypass graft surgery were identified from the New York’s cardiac registry between 1 January 2005 and 31 December 2014. Outcomes were compared for patients receiving SAGs and MAGs over a median follow-up of 6.5 years.

To reduce selection bias, patients in both arms were propensity matched using 38 baseline characteristics. Mortality was the primary endpoint, while secondary endpoints included repeat revascularization and a composite of mortality, acute MI and stroke.

Prior to matching, MAG was used in 20 percent of procedures. No mortality difference was observed at 1 year between matched MAG and SAG patients (2.4 percent vs 2.2 percent; adjusted hazard ratio [AHR], 1.11, 95 percent CI, 0.93–1.32).

However, MAG patients had a lower mortality (12.7 percent vs 14.3 percent; AHR, 0.86, 0.79–0.93), a lower composite outcome (20.2 percent vs 22.8 percent; AHR, 0.88, 0.83–0.93) and a lower repeat revascularization rate (11.7 percent vs 14.6 percent; AHR, 0.80, 0.74–0.87) at 7 years.

Subgroup analysis of MAG patients revealed that those with off-pump surgery, two-vessel disease with right coronary artery disease, recent acute MI, renal dysfunction and aged ≥70 years did not have a lower mortality at 7 years.

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Cardiology - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
Roshini Claire Anthony, 11 Feb 2020

The consumption of processed meat or unprocessed red meat may be associated with a slightly elevated risk of incident cardiovascular disease (CVD)* and all-cause mortality, according to a US study.

Jairia Dela Cruz, 25 Nov 2019
Use of the PCSK9* inhibitor alirocumab in acute coronary syndrome (ACS) patients on a background of high-intensity statin treatment delivers reductions in total hospitalizations and death with corresponding gains in days alive and out of hospital (DAOH), according to the results of prespecified and posthoc analyses of the ODYSSEY OUTCOMES** trial presented at the American Heart Association (AHA) 2019 Scientific Sessions.
Roshini Claire Anthony, 06 Feb 2020

The presence of metabolic syndrome* appears to increase the risk of recurrent venous thromboembolism (VTE)** among patients with deep vein thrombosis (DVT), a recent study showed.

Jairia Dela Cruz, 13 Feb 2020
For regular drinkers with atrial fibrillation (AF), cutting down alcohol consumption confers beneficial effects on both the AF burden and risk of recurrence, according to a recent study.