Most Read Articles
Dr. Joseph Delano Fule Robles, 6 days ago

A recent study conducted by The University of Hong Kong (HKU) revealed that long-term use of proton pump inhibitors (PPIs) is associated with a significantly increased risk of gastric cancer even in patients who have had Helicobacter pylori eradicated. 

5 days ago
The 5-year survival rates for human papillomavirus (HPV)-associated cancers vary greatly according to age and race, with Caucasians and younger patients tending to have better survival, according to a recent US study.
6 days ago
High levels of marijuana exposure appear to not be longitudinally associated with prevalent albuminuria and substantial changes in estimated glomerular filtration rate by cystatin C (eGFRcys), a recent US epidemiological study has shown.
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Men with breast cancer have tumours that are typically of the human epidermal growth factor receptor 2-negative Luminal B subtype and positive for oestrogen receptor, progesterone receptor and androgen receptor, according to the results of the EORTC 10085/TBCRC/BIG/NABCG International Male Breast Cancer Program study.

Mortality up in SLE patients a month after ischaemic stroke

09 Nov 2017

Patients with systemic lupus erythematosus (SLE), compared to those without, have an increased risk of mortality after the first month following an ischaemic stroke, a recent study has found. In addition, functionality becomes poorer at 3 months.

To examine mortality and functionality impairment after stroke in SLE, researchers identified 423 patients with SLE and 1,652 individuals with SLE who developed a first-ever ischaemic or haemorrhagic stroke (1998 to 2013) using Swedish nationwide registers. Patients were followed for 1 year or until all-cause death.

Researchers then estimated the hazard ratio (HR) for death after ischaemic or haemorrhagic stroke and the risk ratio (RR) of functional impairment (dependence in either transferring, toileting or dressing) 3 months following ischaemic stroke.

Twenty-two percent of patients with SLE died a year after stroke compared with 16 percent of those without SLE. There was an increased risk of death for patients with SLE after ischaemic stroke (HR, 1.85; 95 percent CI, 1.39 to 2.45), which was attenuated after controlling for SLE-related comorbidities (HR, 1.41; 1.04 to 1.91).

Furthermore, functional impairment at 3 months increased by almost twofold in patients with SLE (RR, 1.73; 1.16 to 2.57). Those with SLE had an HR for death of 2.30 (1.38 to 3.82) following haemorrhagic stroke, which was elevated even during the first month.

“SLE is associated with all-cause death after haemorrhagic stroke even during the first month,” according to researchers, adding that there is a need for “a shift of focus to patient functionality and prevention of haemorrhagic strokes.”

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Most Read Articles
Dr. Joseph Delano Fule Robles, 6 days ago

A recent study conducted by The University of Hong Kong (HKU) revealed that long-term use of proton pump inhibitors (PPIs) is associated with a significantly increased risk of gastric cancer even in patients who have had Helicobacter pylori eradicated. 

5 days ago
The 5-year survival rates for human papillomavirus (HPV)-associated cancers vary greatly according to age and race, with Caucasians and younger patients tending to have better survival, according to a recent US study.
6 days ago
High levels of marijuana exposure appear to not be longitudinally associated with prevalent albuminuria and substantial changes in estimated glomerular filtration rate by cystatin C (eGFRcys), a recent US epidemiological study has shown.
5 days ago
Men with breast cancer have tumours that are typically of the human epidermal growth factor receptor 2-negative Luminal B subtype and positive for oestrogen receptor, progesterone receptor and androgen receptor, according to the results of the EORTC 10085/TBCRC/BIG/NABCG International Male Breast Cancer Program study.